Monoclonal antibodies and method for detecting dioxins and dibenzofurans

Vanderlaan, Martin; Stanker, Larry H; Watkins, Bruce E; Bailey, Nina R

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Title: Monoclonal antibodies and method for detecting dioxins and dibenzofurans

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Abstract

Compositions of matter are described which include five monoclonal antibodies that react with dioxins and dibenzofurans, and the five hybridomas that produce these monoclonal antibodies. In addition, a method for the use of these antibodies in a sensitive immunoassay for dioxins and dibenzofurans is given, which permits detection of these pollutants in samples at concentrations in the range of a few parts per billion.

Inventors:

Vanderlaan, Martin ^[1]; Stanker, Larry H ^[2]; Watkins, Bruce E ^[2]; Bailey, Nina R ^[3]

San Ramon, CA
Livermore, CA
Berkley, CA

Issue Date:: Sun Jan 01 00:00:00 EST 1989

Research Org.:: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)

OSTI Identifier:: 866820

Patent Number(s):: 4798807

Assignee:: Regents of University of California (Berkeley, CA)

Patent Classifications (CPCs):: C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS

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C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C07K16/44 - against material not provided for elsewhere {, e.g. haptens, metals, DNA, RNA, amino acids}

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S435/948 - using viruses or cell lines
Y10S436/815 - Test for named compound or class of compounds
Y10S530/808 - Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products

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DOE Contract Number:: W-7405-ENG-48

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: monoclonal; antibodies; method; detecting; dioxins; dibenzofurans; compositions; matter; described; five; react; hybridomas; produce; addition; sensitive; immunoassay; permits; detection; pollutants; samples; concentrations; range; billion; permits detection; monoclonal antibodies; sensitive immunoassay; /530/435/436/

Citation Formats


                    Vanderlaan, Martin, Stanker, Larry H, Watkins, Bruce E, and Bailey, Nina R. Monoclonal antibodies and method for detecting dioxins and dibenzofurans.  United States: N. p., 1989. 
        Web.

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                    Vanderlaan, Martin, Stanker, Larry H, Watkins, Bruce E, & Bailey, Nina R. Monoclonal antibodies and method for detecting dioxins and dibenzofurans.  United States.

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                    Vanderlaan, Martin, Stanker, Larry H, Watkins, Bruce E, and Bailey, Nina R. Sun .  
        "Monoclonal antibodies and method for detecting dioxins and dibenzofurans".  United States.  https://www.osti.gov/servlets/purl/866820.

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@article{osti_866820,

  title        = {Monoclonal antibodies and method for detecting dioxins and dibenzofurans},

  author       = {Vanderlaan, Martin and Stanker, Larry H and Watkins, Bruce E and Bailey, Nina R},

  abstractNote = {Compositions of matter are described which include five monoclonal antibodies that react with dioxins and dibenzofurans, and the five hybridomas that produce these monoclonal antibodies. In addition, a method for the use of these antibodies in a sensitive immunoassay for dioxins and dibenzofurans is given, which permits detection of these pollutants in samples at concentrations in the range of a few parts per billion.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Sun Jan 01 00:00:00 EST 1989},

  month        = {Sun Jan 01 00:00:00 EST 1989}

}

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