Method for immunodiagnostic detection of dioxins at low concentrations
Abstract
A method is described for the use of monoclonal antibodies in a sensitive immunoassay for halogenated dioxins and dibenzofurans in industrial samples which contain impurities. Appropriate sample preparation and selective enzyme amplification of the immunoassay sensitivity permits detection of dioxin contaminants in industrial or environmental samples at concentrations in the range of a few parts per trillion.
- Inventors:
-
- (Danville, CA)
- (Livermore, CA)
- (Hochheim am Main, DE)
- (Eppstein/Ts., DE)
- Issue Date:
- Research Org.:
- Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
- OSTI Identifier:
- 869959
- Patent Number(s):
- 5429925
- Assignee:
- Regents of University of California (Oakland, CA) LLNL
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- method; immunodiagnostic; detection; dioxins; concentrations; described; monoclonal; antibodies; sensitive; immunoassay; halogenated; dibenzofurans; industrial; samples; contain; impurities; appropriate; sample; preparation; selective; enzyme; amplification; sensitivity; permits; dioxin; contaminants; environmental; range; trillion; permits detection; environmental sample; sample preparation; monoclonal antibodies; environmental samples; sensitive immunoassay; /435/436/
Citation Formats
Vanderlaan, Martin, Stanker, Larry H., Watkins, Bruce E., Petrovic, Peter, and Gorbach, Siegbert. Method for immunodiagnostic detection of dioxins at low concentrations. United States: N. p., 1995.
Web.
Vanderlaan, Martin, Stanker, Larry H., Watkins, Bruce E., Petrovic, Peter, & Gorbach, Siegbert. Method for immunodiagnostic detection of dioxins at low concentrations. United States.
Vanderlaan, Martin, Stanker, Larry H., Watkins, Bruce E., Petrovic, Peter, and Gorbach, Siegbert. Sun .
"Method for immunodiagnostic detection of dioxins at low concentrations". United States. https://www.osti.gov/servlets/purl/869959.
@article{osti_869959,
title = {Method for immunodiagnostic detection of dioxins at low concentrations},
author = {Vanderlaan, Martin and Stanker, Larry H. and Watkins, Bruce E. and Petrovic, Peter and Gorbach, Siegbert},
abstractNote = {A method is described for the use of monoclonal antibodies in a sensitive immunoassay for halogenated dioxins and dibenzofurans in industrial samples which contain impurities. Appropriate sample preparation and selective enzyme amplification of the immunoassay sensitivity permits detection of dioxin contaminants in industrial or environmental samples at concentrations in the range of a few parts per trillion.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1995},
month = {1}
}
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