skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Method for immunodiagnostic detection of dioxins at low concentrations

Abstract

A method is described for the use of monoclonal antibodies in a sensitive immunoassay for halogenated dioxins and dibenzofurans in industrial samples which contain impurities. Appropriate sample preparation and selective enzyme amplification of the immunoassay sensitivity permits detection of dioxin contaminants in industrial or environmental samples at concentrations in the range of a few parts per trillion.

Inventors:
 [1];  [2];  [2];  [3];  [4]
  1. (Danville, CA)
  2. (Livermore, CA)
  3. (Hochheim am Main, DE)
  4. (Eppstein/Ts., DE)
Issue Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
OSTI Identifier:
869959
Patent Number(s):
5429925
Assignee:
Regents of University of California (Oakland, CA) LLNL
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
method; immunodiagnostic; detection; dioxins; concentrations; described; monoclonal; antibodies; sensitive; immunoassay; halogenated; dibenzofurans; industrial; samples; contain; impurities; appropriate; sample; preparation; selective; enzyme; amplification; sensitivity; permits; dioxin; contaminants; environmental; range; trillion; permits detection; environmental sample; sample preparation; monoclonal antibodies; environmental samples; sensitive immunoassay; /435/436/

Citation Formats

Vanderlaan, Martin, Stanker, Larry H., Watkins, Bruce E., Petrovic, Peter, and Gorbach, Siegbert. Method for immunodiagnostic detection of dioxins at low concentrations. United States: N. p., 1995. Web.
Vanderlaan, Martin, Stanker, Larry H., Watkins, Bruce E., Petrovic, Peter, & Gorbach, Siegbert. Method for immunodiagnostic detection of dioxins at low concentrations. United States.
Vanderlaan, Martin, Stanker, Larry H., Watkins, Bruce E., Petrovic, Peter, and Gorbach, Siegbert. Sun . "Method for immunodiagnostic detection of dioxins at low concentrations". United States. https://www.osti.gov/servlets/purl/869959.
@article{osti_869959,
title = {Method for immunodiagnostic detection of dioxins at low concentrations},
author = {Vanderlaan, Martin and Stanker, Larry H. and Watkins, Bruce E. and Petrovic, Peter and Gorbach, Siegbert},
abstractNote = {A method is described for the use of monoclonal antibodies in a sensitive immunoassay for halogenated dioxins and dibenzofurans in industrial samples which contain impurities. Appropriate sample preparation and selective enzyme amplification of the immunoassay sensitivity permits detection of dioxin contaminants in industrial or environmental samples at concentrations in the range of a few parts per trillion.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1995},
month = {1}
}

Patent:

Save / Share: