Pet imaging of zinc transport
Abstract
A method for producing a solution including a positron emitting zinc cation of .sup.63Zn, and the method comprises bombarding a solution target including .sup.63Cu with high energy protons to produce a solution including a positron emitting zinc cation. A method for detecting or ruling out Alzheimer's disease in a patient comprises administering to a patient a detectable amount of a compound including a positron emitting zinc cation, wherein the zinc cation is targeted to beta-amyloid in the patient, and acquiring an image to detect the presence or absence of beta-amyloid in the patient.
- Inventors:
- Issue Date:
- Research Org.:
- Mayo Foundation for Medical Education and Research, Rochester, MN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1568289
- Patent Number(s):
- 10279054
- Application Number:
- 14/902,744
- Assignee:
- Mayo Foundation for Medical Education and Research (Rochester, MN)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07B - GENERAL METHODS OF ORGANIC CHEMISTRY
- DOE Contract Number:
- SC0008947
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 07/09/2014
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Degrado, Timothy R., Pandey, Mukesh K., Engelbrecht, Hendrik Petrus, and Lowe, Val J. Pet imaging of zinc transport. United States: N. p., 2019.
Web.
Degrado, Timothy R., Pandey, Mukesh K., Engelbrecht, Hendrik Petrus, & Lowe, Val J. Pet imaging of zinc transport. United States.
Degrado, Timothy R., Pandey, Mukesh K., Engelbrecht, Hendrik Petrus, and Lowe, Val J. Tue .
"Pet imaging of zinc transport". United States. https://www.osti.gov/servlets/purl/1568289.
@article{osti_1568289,
title = {Pet imaging of zinc transport},
author = {Degrado, Timothy R. and Pandey, Mukesh K. and Engelbrecht, Hendrik Petrus and Lowe, Val J.},
abstractNote = {A method for producing a solution including a positron emitting zinc cation of .sup.63Zn, and the method comprises bombarding a solution target including .sup.63Cu with high energy protons to produce a solution including a positron emitting zinc cation. A method for detecting or ruling out Alzheimer's disease in a patient comprises administering to a patient a detectable amount of a compound including a positron emitting zinc cation, wherein the zinc cation is targeted to beta-amyloid in the patient, and acquiring an image to detect the presence or absence of beta-amyloid in the patient.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue May 07 00:00:00 EDT 2019},
month = {Tue May 07 00:00:00 EDT 2019}
}
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