Title: Production of hydroxylated fatty acids in genetically modified plants

Abstract

This invention relates to plant fatty acyl hydroxylases. Methods to use conserved amino acid or nucleotide sequences to obtain plant fatty acyl hydroxylases are described. Also described is the use of cDNA clones encoding a plant hydroxylase to produce a family of hydroxylated fatty acids in transgenic plants. In addition, the use of genes encoding fatty acid hydroxylases or desaturases to alter the level of lipid fatty acid unsaturation in transgenic plants is described.

Inventors:

Somerville, Chris ^[1]; Broun, Pierre ^[2]; van de Loo, Frank ^[3]; Boddupalli, Sekhar S ^[4]

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+ Show Inventor Affiliations

1. Portola Valley, CA
2. Burlingame, CA
3. Weston, AU
4. Manchester, MI

Issue Date:

Tue Aug 23 00:00:00 EDT 2011

Research Org.:

Carnegie Institution of Washington (Washington, DC); Monsanto Company, Inc. (St. Louis, MO)

Sponsoring Org.:

USDOE

OSTI Identifier:

1023961

Patent Number(s):

8003855

Application Number:

11/905,067

Assignee:

Carnegie Institution of Washington (Washington, DC)

Patent Classifications (CPCs):

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

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C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

C12N15/8222 - {Developmentally regulated expression systems, tissue, organ specific, temporal or spatial regulation}
C12N15/8247 - {involving modified lipid metabolism, e.g. seed oil composition}
C12N9/0071 - {acting on paired donors with incorporation of molecular oxygen
C12N9/0073 - {with NADH or NADPH as one donor, and incorporation of one atom of oxygen 1.14.13}
C12N9/0083 - {Miscellaneous

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DOE Contract Number:  

FG02-94ER20133

Resource Type:

Patent

Country of Publication:

United States

Language:

English

Subject:

59 BASIC BIOLOGICAL SCIENCES