skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Analyte sensing mediated by adapter/carrier molecules

Abstract

This invention relates to an improved method and system for sensing of one or more analytes. A host molecule, which serves as an adapter/carrier, is used to facilitate interaction between the analyte and the sensor element. A detectable signal is produced reflecting the identity and concentration of analyte present.

Inventors:
 [1];  [1];  [2]
  1. College Station, TX
  2. Bryan, TX
Issue Date:
OSTI Identifier:
874625
Patent Number(s):
6426231
Application Number:
09/441,376
Assignee:
The Texas A&M University System (College Station, TX)
Patent Classifications (CPCs):
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
analyte; sensing; mediated; adaptercarrier; molecules; relates; improved; method; analytes; host; molecule; serves; facilitate; interaction; sensor; element; detectable; signal; produced; reflecting; identity; concentration; /436/204/205/422/435/530/

Citation Formats

Bayley, Hagan, Braha, Orit, and Gu, LiQun. Analyte sensing mediated by adapter/carrier molecules. United States: N. p., 2002. Web.
Bayley, Hagan, Braha, Orit, & Gu, LiQun. Analyte sensing mediated by adapter/carrier molecules. United States.
Bayley, Hagan, Braha, Orit, and Gu, LiQun. Tue . "Analyte sensing mediated by adapter/carrier molecules". United States. https://www.osti.gov/servlets/purl/874625.
@article{osti_874625,
title = {Analyte sensing mediated by adapter/carrier molecules},
author = {Bayley, Hagan and Braha, Orit and Gu, LiQun},
abstractNote = {This invention relates to an improved method and system for sensing of one or more analytes. A host molecule, which serves as an adapter/carrier, is used to facilitate interaction between the analyte and the sensor element. A detectable signal is produced reflecting the identity and concentration of analyte present.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2002},
month = {7}
}

Patent:

Save / Share:

Works referenced in this record:

Porin mutants with new channel properties
journal, July 1998


Protein engineering and the development of generic biosensors
journal, April 1998


A,B,D,F-tetrasubstituted β-cyclodextrin as artificial channel compound
journal, January 1982


Complexation Thermodynamics of Cyclodextrins
journal, July 1998


Staphylococcal alpha-toxin: oligomerization of hydrophilic monomers to form amphiphilic hexamers induced through contact with deoxycholate detergent micelles.
journal, September 1981


Dynamics and Free Energy of Polymers Partitioning into a Nanoscale Pore
journal, January 1996


A biosensor that uses ion-channel switches
journal, June 1997


Novel Water-Soluble β-Cyclodextrin−Calix[4]arene Couples as Fluorescent Sensor Molecules for the Detection of Neutral Analytes
journal, August 1998


Multianalyte microspot immunoassay--microanalytical "compact disk" of the future
journal, November 1991


A sense for landmines
journal, July 1998


Characterization of individual polynucleotide molecules using a membrane channel
journal, November 1996


Crystal structure of the anthrax toxin protective antigen
journal, February 1997


Recognition of neutral species with synthetic receptors
journal, December 1997


Supported Membranes: Scientific and Practical Applications
journal, January 1996


Structure of Staphylococcal alpha -Hemolysin, a Heptameric Transmembrane Pore
journal, December 1996


Channel-type molecular structures. Part 4. Transmembrane transport of alkali-metal ions by ‘bouquet’ molecules
journal, January 1995


Building Doors into Cells
journal, September 1997


Molecular recognition of anions by synthetic receptors
journal, December 1997


Stochastic sensing of organic analytes by a pore-forming protein containing a molecular adapter
journal, April 1999


Towards Artificial Ion Channels: Transport of Alkali Metal Ions across Liposomal Membranes by“Bouquet” Molecules
journal, December 1992


Multiplexed biochemical assays with biological chips
journal, August 1993


A simple method for the determination of the pore radius of ion channels in planar lipid bilayer membranes
journal, September 1992


Trends in odor intensity for human and electronic noses: Relative roles of odorant vapor pressure vs. molecularly specific odorant binding
journal, May 1998


The three-dimensional structure of bovine odorant binding protein and its mechanism of odor recognition
journal, November 1996


Introducing Chemical Transport Selectivity into Gold Nanotubule Membranes
journal, July 1998


Voltammetric study on a condensed monolayer of a long alkyl cyclodextrin derivative as a channel mimetic sensing membrane
journal, April 1993


Single-Molecule Spectroscopy and Dynamics at Room Temperature
journal, January 1996


α-Hemolysin fromStaphylococcus aureus:An Archetype of β-Barrel, Channel-Forming Toxins
journal, January 1998


Voltammetric anion responsive sensors based on modulation of ion permeability through Langmuir-Blodgett films containing synthetic anion receptors
journal, July 1990


The molecular elasticity of the extracellular matrix protein tenascin
journal, May 1998


Designed protein pores as components for biosensors
journal, July 1997


Self-assembled α-hemolysin pores in an S-layer-supported lipid bilayer
journal, March 1998


Emerging techniques for investigating molecular interactions at lipid membranes
journal, November 1998