Microfluidic systems, pumps, valves, fluidic chips thereof, and applications of same
Abstract
Microfluidic systems, pumps, valves and applications of the same are provided. The microfluidic system may be a pump or a valve having a fluidic chip and an actuator controlling the opening and closing of the fluidic channel in the fluidic chip. The actuator may be disposed to tilt from the fluidic chip, forming a tilted-rotor peristaltic pump. Alternatively, the actuator may be a rolling ball actuator, and different fluidic chips may be used in different applications. For example, the fluidic chip may be a spiral pump chip having spiral channels, a rotary peristaltic pump chip having multiple output channels, or a multi-port valve chip having one port interconnected with multiple different ports. An analytical valve chip may switchably interconnect bioreactor and rinse/calibration input channels to sensor and waste output channels. The actuator of a random-access valve can move from one valve position to another without opening or closing intermediate ones.
- Inventors:
- Issue Date:
- Research Org.:
- Vanderbilt Univ., Nashville, TN (United States)
- Sponsoring Org.:
- USDOE; National Institutes of Health (NIH); US Environmental Protection Agency (EPA); Intelligence Advanced Research Projects Activity; Defense Threat Reduction Agency (DTRA)
- OSTI Identifier:
- 1987094
- Patent Number(s):
- 11565256
- Application Number:
- 17/623,350
- Assignee:
- Vanderbilt University (Nashville, TN)
- DOE Contract Number:
- 468746; 5UG3TR002097-02; 83573601; CBMXCEL-XL1-2-001; HHSN44C; U01CA202229
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 06/29/2020
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Reiserer, Ronald S., Schaffer, David K., Samson, Philip C., Markov, Dmitry A., Geuy, Michael, McCawley, Lisa J., and Wikswo, John P. Microfluidic systems, pumps, valves, fluidic chips thereof, and applications of same. United States: N. p., 2023.
Web.
Reiserer, Ronald S., Schaffer, David K., Samson, Philip C., Markov, Dmitry A., Geuy, Michael, McCawley, Lisa J., & Wikswo, John P. Microfluidic systems, pumps, valves, fluidic chips thereof, and applications of same. United States.
Reiserer, Ronald S., Schaffer, David K., Samson, Philip C., Markov, Dmitry A., Geuy, Michael, McCawley, Lisa J., and Wikswo, John P. Tue .
"Microfluidic systems, pumps, valves, fluidic chips thereof, and applications of same". United States. https://www.osti.gov/servlets/purl/1987094.
@article{osti_1987094,
title = {Microfluidic systems, pumps, valves, fluidic chips thereof, and applications of same},
author = {Reiserer, Ronald S. and Schaffer, David K. and Samson, Philip C. and Markov, Dmitry A. and Geuy, Michael and McCawley, Lisa J. and Wikswo, John P.},
abstractNote = {Microfluidic systems, pumps, valves and applications of the same are provided. The microfluidic system may be a pump or a valve having a fluidic chip and an actuator controlling the opening and closing of the fluidic channel in the fluidic chip. The actuator may be disposed to tilt from the fluidic chip, forming a tilted-rotor peristaltic pump. Alternatively, the actuator may be a rolling ball actuator, and different fluidic chips may be used in different applications. For example, the fluidic chip may be a spiral pump chip having spiral channels, a rotary peristaltic pump chip having multiple output channels, or a multi-port valve chip having one port interconnected with multiple different ports. An analytical valve chip may switchably interconnect bioreactor and rinse/calibration input channels to sensor and waste output channels. The actuator of a random-access valve can move from one valve position to another without opening or closing intermediate ones.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2023},
month = {1}
}
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