Check valves for microfluidic systems and methods thereof

Ball, Cameron Scott; Renzi, Ronald F.; Meagher, Robert

Title: Check valves for microfluidic systems and methods thereof

Abstract

The present invention relates to microfluidic check valves, as well as fluidic cartridges including such check valves. In particular examples, the check valve includes a pre-stressed spring formed from a planar substrate. Various characteristics of the valves, such as size, profile, opening pressure, etc., can be tuned to provide desired performance when employed within a fluidic cartridge.

Inventors:: Ball, Cameron Scott; Renzi, Ronald F.; Meagher, Robert

Issue Date:: 2019-11-19

Research Org.:: Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1600287

Patent Number(s):: 10478818

Application Number:: 15/447,581

Assignee:: National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, NM)

Patent Classifications (CPCs):: B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE

F - MECHANICAL ENGINEERING F16 - ENGINEERING ELEMENTS AND UNITS F16K - VALVES

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B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
B01L2300/049 - Valves integrated in closure
B01L2200/12 - Specific details about manufacturing devices

F - MECHANICAL ENGINEERING F16 - ENGINEERING ELEMENTS AND UNITS F16K - VALVES
F16K99/0015 - {Diaphragm or membrane valves}
F16K99/0009 - {the valve element held by multiple arms}

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
B01L3/502738 - {characterised by integrated valves

F - MECHANICAL ENGINEERING F16 - ENGINEERING ELEMENTS AND UNITS F16K - VALVES
F16K2099/0094 - {Micropumps}
F16K2099/008 - {Multi-layer fabrications}
F16K99/0057 - {the fluid being the circulating fluid itself, e.g. check valves}

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
B01L3/50273 - {characterised by the means or forces applied to move the fluids
B01L2400/0487 - fluid pressure, pneumatics
B01L2400/0605 - check valves

F - MECHANICAL ENGINEERING F16 - ENGINEERING ELEMENTS AND UNITS F16K - VALVES
F16K2099/0084 - {Chemistry or biology, e.g. "lab-on-a-chip" technology}

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
B01L2300/0887 - Laminated structure
B01L3/502707 - {characterised by the manufacture of the container or its components
B01L3/502715 - {characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces}
B01L2200/10 - Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept

F - MECHANICAL ENGINEERING F16 - ENGINEERING ELEMENTS AND UNITS F16K - VALVES
F16K99/0005 - {Lift valves}

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DOE Contract Number:: AC04-94AL85000

Resource Type:: Patent

Resource Relation:: Patent File Date: 03/02/2017

Country of Publication:: United States

Language:: English

Subject:: 42 ENGINEERING

Citation Formats


                    Ball, Cameron Scott, Renzi, Ronald F., and Meagher, Robert. Check valves for microfluidic systems and methods thereof.  United States: N. p., 2019. 
        Web.

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                    Ball, Cameron Scott, Renzi, Ronald F., & Meagher, Robert. Check valves for microfluidic systems and methods thereof.  United States.

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                    Ball, Cameron Scott, Renzi, Ronald F., and Meagher, Robert. Tue .  
        "Check valves for microfluidic systems and methods thereof".  United States.  https://www.osti.gov/servlets/purl/1600287.

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@article{osti_1600287,

  title        = {Check valves for microfluidic systems and methods thereof},

  author       = {Ball, Cameron Scott and Renzi, Ronald F. and Meagher, Robert},

  abstractNote = {The present invention relates to microfluidic check valves, as well as fluidic cartridges including such check valves. In particular examples, the check valve includes a pre-stressed spring formed from a planar substrate. Various characteristics of the valves, such as size, profile, opening pressure, etc., can be tuned to provide desired performance when employed within a fluidic cartridge.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2019},

  month        = {11}

}

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Title: Check valves for microfluidic systems and methods thereof

Abstract

Citation Formats

Edge compression manifold apparatus patent, December 2004

Capillary interconnect device patent, December 2007

Additive-mixing fuel-injection system for internal combustion engines patent, February 2019

Method and apparatus for calibrating a particle emissions monitor patent, July 1998

Multidimensional bioseparation with modular microfluidics patent, August 2013

Fluid delivery manifolds and microfluidic systems patent, February 2017

Edge compression manifold apparatus patent, February 2007

Microfluidic structures and methods for integrating a functional component into a microfluidic device patent, April 2008

Valve, Layer Structure Comprising a First and a Second Valve, Micropump and Method of Producing Valve patent-application, March 2013

Modular optical detector system patent, February 2006

High temperature flow-through device for rapid solubilization and analysis patent, April 2013

Capillary interconnect device patent, November 2013

Microvalve patent, July 2005

Ion chamber based neutron detectors patent, December 2014

Micromanifold assembly patent, June 2009

Micromanifold assembly patent, April 2012

Portable apparatus for separating sample and detecting target analytes patent, November 2008

Fluid injection microvalve patent, November 2005

Particle sorter comprising a fluid displacer in a closed-loop fluid circuit patent, April 2012

Microelectroporation device for genomic screening patent, September 2014

Multiplexed microfluidic approach for nucleic acid enrichment patent, April 2016

Compact radiation detector patent, June 2018

High pressure capillary connector patent, August 2005

Compact ion chamber based neutron detector patent, October 2015

Method for forming polymerized microfluidic devices patent, March 2013

Methods for integrating a functional component into a microfluidic device patent, August 2014

Micropores and methods of making and using thereof patent, August 2016

Microfluidic hubs, systems, and methods for interface fluidic modules patent, January 2015

Method for forming polymerized microfluidic devices patent, November 2011

Method for enhanced control of welding processes patent, July 2000

Micropores and methods of making and using thereof patent, November 2013

System for particle concentration and detection patent, March 2013

Virtual environment tactile system patent, December 1996

High temperature flow-through device for rapid solubilization and analysis patent, September 2009

Edge compression manifold apparatus
patent, December 2004

Capillary interconnect device
patent, December 2007

Additive-mixing fuel-injection system for internal combustion engines
patent, February 2019

Method and apparatus for calibrating a particle emissions monitor
patent, July 1998

Multidimensional bioseparation with modular microfluidics
patent, August 2013

Fluid delivery manifolds and microfluidic systems
patent, February 2017

Edge compression manifold apparatus
patent, February 2007

Microfluidic structures and methods for integrating a functional component into a microfluidic device
patent, April 2008

Valve, Layer Structure Comprising a First and a Second Valve, Micropump and Method of Producing Valve
patent-application, March 2013

Modular optical detector system
patent, February 2006

High temperature flow-through device for rapid solubilization and analysis
patent, April 2013

Capillary interconnect device
patent, November 2013

Microvalve
patent, July 2005

Ion chamber based neutron detectors
patent, December 2014

Micromanifold assembly
patent, June 2009

Micromanifold assembly
patent, April 2012

Portable apparatus for separating sample and detecting target analytes
patent, November 2008

Fluid injection microvalve
patent, November 2005

Particle sorter comprising a fluid displacer in a closed-loop fluid circuit
patent, April 2012

Microelectroporation device for genomic screening
patent, September 2014

Multiplexed microfluidic approach for nucleic acid enrichment
patent, April 2016

Compact radiation detector
patent, June 2018

High pressure capillary connector
patent, August 2005

Compact ion chamber based neutron detector
patent, October 2015

Method for forming polymerized microfluidic devices
patent, March 2013

Methods for integrating a functional component into a microfluidic device
patent, August 2014

Micropores and methods of making and using thereof
patent, August 2016

Microfluidic hubs, systems, and methods for interface fluidic modules
patent, January 2015

Method for forming polymerized microfluidic devices
patent, November 2011

Method for enhanced control of welding processes
patent, July 2000

Micropores and methods of making and using thereof
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System for particle concentration and detection
patent, March 2013

Virtual environment tactile system
patent, December 1996

High temperature flow-through device for rapid solubilization and analysis
patent, September 2009