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Title: Genetically-modified bacteria for conversion of organic compounds to butanol and methods of use

Abstract

This disclosure provides a genetically-modified bacterium from the genus Megasphaera that comprises an exogenous nucleic acid encoding a bifunctional aldehyde/alcohol dehydrogenase that produces butanol as the final product. The disclosure further provides methods for producing butanol using such genetically-modified bacterium.

Inventors:
;
Issue Date:
Research Org.:
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1986678
Patent Number(s):
11466296
Application Number:
16/934,359
Assignee:
UT-Battelle LLC (Oak Ridge, TN)
DOE Contract Number:  
AC05-00OR22725
Resource Type:
Patent
Resource Relation:
Patent File Date: 07/21/2020
Country of Publication:
United States
Language:
English

Citation Formats

Guss, Adam M., and Riley, Lauren A. Genetically-modified bacteria for conversion of organic compounds to butanol and methods of use. United States: N. p., 2022. Web.
Guss, Adam M., & Riley, Lauren A. Genetically-modified bacteria for conversion of organic compounds to butanol and methods of use. United States.
Guss, Adam M., and Riley, Lauren A. Tue . "Genetically-modified bacteria for conversion of organic compounds to butanol and methods of use". United States. https://www.osti.gov/servlets/purl/1986678.
@article{osti_1986678,
title = {Genetically-modified bacteria for conversion of organic compounds to butanol and methods of use},
author = {Guss, Adam M. and Riley, Lauren A.},
abstractNote = {This disclosure provides a genetically-modified bacterium from the genus Megasphaera that comprises an exogenous nucleic acid encoding a bifunctional aldehyde/alcohol dehydrogenase that produces butanol as the final product. The disclosure further provides methods for producing butanol using such genetically-modified bacterium.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Oct 11 00:00:00 EDT 2022},
month = {Tue Oct 11 00:00:00 EDT 2022}
}

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patent-application, October 2019


Production of medium-chain carboxylic acids by Megasphaera sp. MH with supplemental electron acceptors
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