Advanced drug development and manufacturing
Abstract
X-ray fluorescence (XRF) spectrometry has been used for detecting binding events and measuring binding selectivities between chemicals and receptors. XRF may also be used for estimating the therapeutic index of a chemical. For estimating the binding selectivities of a chemical versus chemical analogs, for measuring post translational modification of proteins, and for drug manufacturing.
- Inventors:
- Issue Date:
- Research Org.:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1771770
- Patent Number(s):
- 10877035
- Application Number:
- 14/693,094
- Assignee:
- ICAGEN, LLC (San Diego, CA)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC52-06NA25396
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 04/22/2015
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Birnbaum, Eva R., Koppisch, Andrew T., Baldwin, Sharon M., Warner, Benjamin P., McCleskey, T. Mark, Berger, Jennifer A., Stewart, Jeffrey J., Harris, Michael N., and Burrell, Anthony K. Advanced drug development and manufacturing. United States: N. p., 2020.
Web.
Birnbaum, Eva R., Koppisch, Andrew T., Baldwin, Sharon M., Warner, Benjamin P., McCleskey, T. Mark, Berger, Jennifer A., Stewart, Jeffrey J., Harris, Michael N., & Burrell, Anthony K. Advanced drug development and manufacturing. United States.
Birnbaum, Eva R., Koppisch, Andrew T., Baldwin, Sharon M., Warner, Benjamin P., McCleskey, T. Mark, Berger, Jennifer A., Stewart, Jeffrey J., Harris, Michael N., and Burrell, Anthony K. Tue .
"Advanced drug development and manufacturing". United States. https://www.osti.gov/servlets/purl/1771770.
@article{osti_1771770,
title = {Advanced drug development and manufacturing},
author = {Birnbaum, Eva R. and Koppisch, Andrew T. and Baldwin, Sharon M. and Warner, Benjamin P. and McCleskey, T. Mark and Berger, Jennifer A. and Stewart, Jeffrey J. and Harris, Michael N. and Burrell, Anthony K.},
abstractNote = {X-ray fluorescence (XRF) spectrometry has been used for detecting binding events and measuring binding selectivities between chemicals and receptors. XRF may also be used for estimating the therapeutic index of a chemical. For estimating the binding selectivities of a chemical versus chemical analogs, for measuring post translational modification of proteins, and for drug manufacturing.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {12}
}
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