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Title: Advanced drug development and manufacturing

Abstract

X-ray fluorescence (XRF) spectrometry has been used for detecting binding events and measuring binding selectivities between chemicals and receptors. XRF may also be used for estimating the therapeutic index of a chemical. For estimating the binding selectivities of a chemical versus chemical analogs, for measuring post translational modification of proteins, and for drug manufacturing.

Inventors:
; ; ; ; ; ; ; ;
Issue Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1771770
Patent Number(s):
10877035
Application Number:
14/693,094
Assignee:
ICAGEN, LLC (San Diego, CA)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC52-06NA25396
Resource Type:
Patent
Resource Relation:
Patent File Date: 04/22/2015
Country of Publication:
United States
Language:
English

Citation Formats

Birnbaum, Eva R., Koppisch, Andrew T., Baldwin, Sharon M., Warner, Benjamin P., McCleskey, T. Mark, Berger, Jennifer A., Stewart, Jeffrey J., Harris, Michael N., and Burrell, Anthony K. Advanced drug development and manufacturing. United States: N. p., 2020. Web.
Birnbaum, Eva R., Koppisch, Andrew T., Baldwin, Sharon M., Warner, Benjamin P., McCleskey, T. Mark, Berger, Jennifer A., Stewart, Jeffrey J., Harris, Michael N., & Burrell, Anthony K. Advanced drug development and manufacturing. United States.
Birnbaum, Eva R., Koppisch, Andrew T., Baldwin, Sharon M., Warner, Benjamin P., McCleskey, T. Mark, Berger, Jennifer A., Stewart, Jeffrey J., Harris, Michael N., and Burrell, Anthony K. Tue . "Advanced drug development and manufacturing". United States. https://www.osti.gov/servlets/purl/1771770.
@article{osti_1771770,
title = {Advanced drug development and manufacturing},
author = {Birnbaum, Eva R. and Koppisch, Andrew T. and Baldwin, Sharon M. and Warner, Benjamin P. and McCleskey, T. Mark and Berger, Jennifer A. and Stewart, Jeffrey J. and Harris, Michael N. and Burrell, Anthony K.},
abstractNote = {X-ray fluorescence (XRF) spectrometry has been used for detecting binding events and measuring binding selectivities between chemicals and receptors. XRF may also be used for estimating the therapeutic index of a chemical. For estimating the binding selectivities of a chemical versus chemical analogs, for measuring post translational modification of proteins, and for drug manufacturing.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {12}
}

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