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Title: Micro-fluidic partitioning between polymeric sheets for chemical amplification and processing

Abstract

A system for fluid partitioning for chemical amplification or other chemical processing or separations of a sample, comprising a first dispenser of a first polymeric sheet, wherein the first polymeric sheet contains chambers; a second dispenser of a second polymeric sheet wherein the first dispenser and the second dispenser are positioned so that the first polymeric sheet and the second polymeric sheet become parallel; a dispenser of the fluid positioned to dispense the fluid between the first polymeric sheet and the second polymeric sheet; and a seal unit that seals the first polymeric sheet and the second polymeric sheet together thereby sealing the sample between the first polymeric sheet and the second polymeric sheet and partitioning the fluid for chemical amplification or other chemical processing or separations.

Inventors:
Issue Date:
Research Org.:
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1340580
Patent Number(s):
9550186
Application Number:
14/695,968
Assignee:
Lawrence Livermore National Security, LLC (Livermore, CA)
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
B - PERFORMING OPERATIONS B32 - LAYERED PRODUCTS B32B - LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
DOE Contract Number:  
AC52-07NA27344
Resource Type:
Patent
Resource Relation:
Patent File Date: 2015 Apr 24
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Anderson, Brian L. Micro-fluidic partitioning between polymeric sheets for chemical amplification and processing. United States: N. p., 2017. Web.
Anderson, Brian L. Micro-fluidic partitioning between polymeric sheets for chemical amplification and processing. United States.
Anderson, Brian L. Tue . "Micro-fluidic partitioning between polymeric sheets for chemical amplification and processing". United States. https://www.osti.gov/servlets/purl/1340580.
@article{osti_1340580,
title = {Micro-fluidic partitioning between polymeric sheets for chemical amplification and processing},
author = {Anderson, Brian L.},
abstractNote = {A system for fluid partitioning for chemical amplification or other chemical processing or separations of a sample, comprising a first dispenser of a first polymeric sheet, wherein the first polymeric sheet contains chambers; a second dispenser of a second polymeric sheet wherein the first dispenser and the second dispenser are positioned so that the first polymeric sheet and the second polymeric sheet become parallel; a dispenser of the fluid positioned to dispense the fluid between the first polymeric sheet and the second polymeric sheet; and a seal unit that seals the first polymeric sheet and the second polymeric sheet together thereby sealing the sample between the first polymeric sheet and the second polymeric sheet and partitioning the fluid for chemical amplification or other chemical processing or separations.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jan 24 00:00:00 EST 2017},
month = {Tue Jan 24 00:00:00 EST 2017}
}

Works referenced in this record:

Chemical amplification based on fluid partitioning
patent, May 2006


Polymer-based platform for microfluidic systems
patent, October 2009


Chemical amplification based on fluid partitioning in an immiscible liquid
patent, September 2010


Microfluidic reaction apparatus for high throughput screening
patent, October 2010


Microfluidic device and methods of using same
patent, November 2010