Methods for producing Cu-67 radioisotope with use of a ceramic capsule for medical applications
Abstract
The present invention provides a method for producing Cu67 radioisotope suitable for use in medical applications. The method comprises irradiating a metallic zinc-68 (Zn68) target within a sealed ceramic capsule with a high energy gamma ray beam. After irradiation, the Cu67 is isolated from the Zn68 by any suitable method (e.g. chemical and or physical separation). In a preferred embodiment, the Cu67 is isolated by sublimation of the zinc in a ceramic sublimation tube to afford a copper residue containing Cu67. The Cu67 can be further purified by chemical means.
- Inventors:
- Issue Date:
- Research Org.:
- Argonne National Lab. (ANL), Argonne, IL (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1248479
- Patent Number(s):
- 9312037
- Application Number:
- 13/399,082
- Assignee:
- UCHICAGO ARGONNE, LLC (Chicago, IL)
- Patent Classifications (CPCs):
-
H - ELECTRICITY H05 - ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR H05H - PLASMA TECHNIQUE
G - PHYSICS G21 - NUCLEAR PHYSICS G21K - TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR
- DOE Contract Number:
- AC02-06CH11357
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2012 Feb 17
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 07 ISOTOPE AND RADIATION SOURCES; 60 APPLIED LIFE SCIENCES
Citation Formats
Ehst, David A., and Willit, James L. Methods for producing Cu-67 radioisotope with use of a ceramic capsule for medical applications. United States: N. p., 2016.
Web.
Ehst, David A., & Willit, James L. Methods for producing Cu-67 radioisotope with use of a ceramic capsule for medical applications. United States.
Ehst, David A., and Willit, James L. Tue .
"Methods for producing Cu-67 radioisotope with use of a ceramic capsule for medical applications". United States. https://www.osti.gov/servlets/purl/1248479.
@article{osti_1248479,
title = {Methods for producing Cu-67 radioisotope with use of a ceramic capsule for medical applications},
author = {Ehst, David A. and Willit, James L.},
abstractNote = {The present invention provides a method for producing Cu67 radioisotope suitable for use in medical applications. The method comprises irradiating a metallic zinc-68 (Zn68) target within a sealed ceramic capsule with a high energy gamma ray beam. After irradiation, the Cu67 is isolated from the Zn68 by any suitable method (e.g. chemical and or physical separation). In a preferred embodiment, the Cu67 is isolated by sublimation of the zinc in a ceramic sublimation tube to afford a copper residue containing Cu67. The Cu67 can be further purified by chemical means.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {4}
}
Works referenced in this record:
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Chemical modification of silica surface by immobilization of functional groups for extractive concentration of metal ions
journal, April 2004
- Jal, P.
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The production of copper 67 from natural zinc using a linear accelerator
journal, November 1970
- Marceau, N.; Kruck, T. P. A.; McConnell, D. B.
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The Preparation of High Specific Activity Copper 64
journal, January 1964
- Fritze, K.
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