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Title: Methods for making and processing metal targets for producing Cu-67 radioisotope for medical applications

Abstract

The present invention provides a method for producing Cu67 radioisotope suitable for use in medical applications. The method comprises irradiating a metallic zinc-68 (Zn68) target with a high energy gamma ray beam. After irradiation, the Cu67 is isolated from the Zn68 by any suitable method (e.g., chemical and/or physical separation). In a preferred embodiment, the Cu67 is isolated by sublimation of the zinc (e.g., at about 500-700° C. under reduced pressure) to afford a copper residue containing Cu67. The Cu67 can be further purified by chemical means (i.e., dissolution in acid, followed by ion exchange).

Inventors:
;
Issue Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1531870
Patent Number(s):
8,526,561
Application Number:
12/462,099
Assignee:
UChicago Argonne, LLC (Chicago, IL)
DOE Contract Number:  
AC02-06CH11357; W-31-109-ENG-38
Resource Type:
Patent
Resource Relation:
Patent File Date: 2009-07-29
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; 07 ISOTOPE AND RADIATION SOURCES

Citation Formats

Ehst, David A., and Bowers, Delbert L. Methods for making and processing metal targets for producing Cu-67 radioisotope for medical applications. United States: N. p., 2013. Web.
Ehst, David A., & Bowers, Delbert L. Methods for making and processing metal targets for producing Cu-67 radioisotope for medical applications. United States.
Ehst, David A., and Bowers, Delbert L. Tue . "Methods for making and processing metal targets for producing Cu-67 radioisotope for medical applications". United States. https://www.osti.gov/servlets/purl/1531870.
@article{osti_1531870,
title = {Methods for making and processing metal targets for producing Cu-67 radioisotope for medical applications},
author = {Ehst, David A. and Bowers, Delbert L.},
abstractNote = {The present invention provides a method for producing Cu67 radioisotope suitable for use in medical applications. The method comprises irradiating a metallic zinc-68 (Zn68) target with a high energy gamma ray beam. After irradiation, the Cu67 is isolated from the Zn68 by any suitable method (e.g., chemical and/or physical separation). In a preferred embodiment, the Cu67 is isolated by sublimation of the zinc (e.g., at about 500-700° C. under reduced pressure) to afford a copper residue containing Cu67. The Cu67 can be further purified by chemical means (i.e., dissolution in acid, followed by ion exchange).},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2013},
month = {9}
}

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Works referenced in this record:

Production of radioisotopes with a high specific activity by isotopic conversion
patent, September 1999


Method of producing molybdenum-99
patent, July 1998


Production of radioisotopes with a high specific activity by isotopic conversion
patent, March 2001


    Works referencing / citing this record:

    Production of copper-67 from an enriched zinc-68 target
    patent, June 2018