Isolated nucleic acids encoding antipathogenic polypeptides and uses thereof
Abstract
Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include amino acid sequences, and variants and fragments thereof, for antipathogenic polypeptides that were isolated from fungal fermentation broths. Nucleic acids that encode the antipathogenic polypeptides are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided. Transformed plants, plant cells, seeds, and microorganisms comprising a nucleotide sequence that encodes an antipathogenic polypeptide of the invention are also disclosed.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1176246
- Patent Number(s):
- 7700832
- Application Number:
- 12/265,461
- Assignee:
- Pioneer Hi-Bred International, Inc. (Johnston, IA); E.I. du Pont de Nemours and Company (Wilmington, DE); The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- AC02-05CH11231
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2008 Nov 05
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Altier, Daniel J., Crane, Virginia C., Ellanskaya, Irina, Ellanskaya, Natalia, Gilliam, Jacob T., Hunter-Cevera, Jennie, Presnail, James K., Schepers, Eric J., Simmons, Carl R., Torok, Tamas, and Yalpani, Nasser. Isolated nucleic acids encoding antipathogenic polypeptides and uses thereof. United States: N. p., 2010.
Web.
Altier, Daniel J., Crane, Virginia C., Ellanskaya, Irina, Ellanskaya, Natalia, Gilliam, Jacob T., Hunter-Cevera, Jennie, Presnail, James K., Schepers, Eric J., Simmons, Carl R., Torok, Tamas, & Yalpani, Nasser. Isolated nucleic acids encoding antipathogenic polypeptides and uses thereof. United States.
Altier, Daniel J., Crane, Virginia C., Ellanskaya, Irina, Ellanskaya, Natalia, Gilliam, Jacob T., Hunter-Cevera, Jennie, Presnail, James K., Schepers, Eric J., Simmons, Carl R., Torok, Tamas, and Yalpani, Nasser. Tue .
"Isolated nucleic acids encoding antipathogenic polypeptides and uses thereof". United States. https://www.osti.gov/servlets/purl/1176246.
@article{osti_1176246,
title = {Isolated nucleic acids encoding antipathogenic polypeptides and uses thereof},
author = {Altier, Daniel J. and Crane, Virginia C. and Ellanskaya, Irina and Ellanskaya, Natalia and Gilliam, Jacob T. and Hunter-Cevera, Jennie and Presnail, James K. and Schepers, Eric J. and Simmons, Carl R. and Torok, Tamas and Yalpani, Nasser},
abstractNote = {Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include amino acid sequences, and variants and fragments thereof, for antipathogenic polypeptides that were isolated from fungal fermentation broths. Nucleic acids that encode the antipathogenic polypeptides are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided. Transformed plants, plant cells, seeds, and microorganisms comprising a nucleotide sequence that encodes an antipathogenic polypeptide of the invention are also disclosed.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 20 00:00:00 EDT 2010},
month = {Tue Apr 20 00:00:00 EDT 2010}
}
Works referenced in this record:
Functional Analysis of Conserved Histidines in ADP-Glucose Pyrophosphorylase from Escherichia coli
journal, March 1998
- Hill, Margaret A.; Preiss, Jack
- Biochemical and Biophysical Research Communications, Vol. 244, Issue 2, p. 573-577
Transforming growth factor alpha: mutation of aspartic acid 47 and leucine 48 results in different biological activities.
journal, March 1988
- Lazar, E.; Watanabe, S.; Dalton, S.
- Molecular and Cellular Biology, Vol. 8, Issue 3, p. 1247-1252
New insights into the target site and mode of action of the antifungal protein of Aspergillus giganteus
journal, January 2005
- Theis, Torsten; Marx, Florentine; Salvenmoser, Willibald
- Research in Microbiology, Vol. 156, Issue 1
Isolation and Characterization of a Novel Antifungal Peptide from Aspergillus niger
journal, October 1999
- Gun Lee, Dong; Yub Shin, Song; Maeng, Cheol-Young
- Biochemical and Biophysical Research Communications, Vol. 263, Issue 3
In Defense against Pathogens. Both Plant Sentinels and Foot Soldiers Need to Know the Enemy: Fig. 1.
journal, April 2003
- Veronese, Paola; Ruiz, Maria T.; Coca, Maria A.
- Plant Physiology, Vol. 131, Issue 4
Genetically engineered stem rust resistance in barley using the Rpg1 gene
journal, December 2002
- Horvath, H.; Rostoks, N.; Brueggeman, R.
- Proceedings of the National Academy of Sciences, Vol. 100, Issue 1
Mycotoxines : effets sur la santé et interactions avec d'autres composants organiques
journal, April 2006
- Reboux, G.
- Revue Française d'Allergologie et d'Immunologie Clinique, Vol. 46, Issue 3
Purification, Characterisation and cDNA Cloning of an Antimicrobial Peptide from Macadamia Integrifolia
journal, March 1997
- Marcus, John P.; Goulter, Ken C.; Green, Jodie L.
- European Journal of Biochemistry, Vol. 244, Issue 3
Interactions of Pseudomonas fluorescens strain E6 with Ornamental Plants and Its Effect on the Composition of Root-Colonizing Microflora
journal, January 1986
- Yuen, G. Y.
- Phytopathology, Vol. 76, Issue 2
Occurrence of Species of Aspergillus and Penicillium in Roots of Wheat and Ryegrass and Their Effects on Root Rot Caused by Gaeumannomyces graminis var. Tritici
journal, January 1988
- Dewan, Mm; Sivasithamparam, K.
- Australian Journal of Botany, Vol. 36, Issue 6
Unexpected homology between inducible cell wall protein QID74 of filamentous fungi and BR3 salivary protein of the insect Chironomus
journal, May 1998
- Rey, M.; Ohno, S.; Pintor-Toro, J. A.
- Proceedings of the National Academy of Sciences, Vol. 95, Issue 11
Sensitivity of different Zygomycetes to the Penicillium chrysogenum antifungal protein (PAF): Effects of PAF on Zygomycetes
journal, April 2005
- Galgóczy, László; Papp, Tamás; Leiter, Éva
- Journal of Basic Microbiology, Vol. 45, Issue 2
Functional Domain Analysis of the Yeast ABC Transporter Ycf1p by Site-directed Mutagenesis
journal, August 1999
- Falcón-Pérez, Juan M.; Mazón, Marı́a J.; Molano, Jesús
- Journal of Biological Chemistry, Vol. 274, Issue 33