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Title: Nucleic acids encoding antifungal polypeptides and uses thereof

Abstract

Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include an amino acid sequence, and variants and fragments thereof, for an antipathogenic polypeptide that was isolated from a fungal fermentation broth. Nucleic acid molecules that encode the antipathogenic polypeptides of the invention, and antipathogenic domains thereof, are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided. Transformed plants, plant cells, seeds, and microorganisms comprising a nucleotide sequence that encodes an antipathogenic polypeptide of the invention are also disclosed.

Inventors:
 [1];  [2];  [3];  [4];  [5];  [6];  [7];  [8];  [9]
  1. Granger, IA
  2. Kyiv, UA
  3. Norwalk, IA
  4. Elliott City, MD
  5. Avondale, PA
  6. Port Deposit, MD
  7. Des Moines, IA
  8. Richmond, CA
  9. Johnston, IA
Issue Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1014929
Patent Number(s):
7825294
Application Number:
US Patent Application 12/503,952
Assignee:
Pioneer Hi-Bred International, Inc. (Johnston, IA); E.I. du Pont de Nemours and Company (Wilmington, DE); The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
A - HUMAN NECESSITIES A01 - AGRICULTURE A01N - PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF
DOE Contract Number:  
AC02-05CH11231
Resource Type:
Patent
Country of Publication:
United States
Language:
English

Citation Formats

Altier, Daniel J, Ellanskaya, I A, Gilliam, Jacob T, Hunter-Cevera, Jennie, Presnail, James K, Schepers, Eric, Simmons, Carl R, Torok, Tamas, and Yalpani, Nasser. Nucleic acids encoding antifungal polypeptides and uses thereof. United States: N. p., 2010. Web.
Altier, Daniel J, Ellanskaya, I A, Gilliam, Jacob T, Hunter-Cevera, Jennie, Presnail, James K, Schepers, Eric, Simmons, Carl R, Torok, Tamas, & Yalpani, Nasser. Nucleic acids encoding antifungal polypeptides and uses thereof. United States.
Altier, Daniel J, Ellanskaya, I A, Gilliam, Jacob T, Hunter-Cevera, Jennie, Presnail, James K, Schepers, Eric, Simmons, Carl R, Torok, Tamas, and Yalpani, Nasser. Tue . "Nucleic acids encoding antifungal polypeptides and uses thereof". United States. https://www.osti.gov/servlets/purl/1014929.
@article{osti_1014929,
title = {Nucleic acids encoding antifungal polypeptides and uses thereof},
author = {Altier, Daniel J and Ellanskaya, I A and Gilliam, Jacob T and Hunter-Cevera, Jennie and Presnail, James K and Schepers, Eric and Simmons, Carl R and Torok, Tamas and Yalpani, Nasser},
abstractNote = {Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include an amino acid sequence, and variants and fragments thereof, for an antipathogenic polypeptide that was isolated from a fungal fermentation broth. Nucleic acid molecules that encode the antipathogenic polypeptides of the invention, and antipathogenic domains thereof, are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided. Transformed plants, plant cells, seeds, and microorganisms comprising a nucleotide sequence that encodes an antipathogenic polypeptide of the invention are also disclosed.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2010},
month = {11}
}

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Works referenced in this record:

Unexpected homology between inducible cell wall protein QID74 of filamentous fungi and BR3 salivary protein of the insect Chironomus
journal, May 1998