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Title: Helical synthetic peptides that stimulate cellular cholesterol efflux

Abstract

The present invention provides peptides comprising at least one amphipathic alpha helix and having an cholesterol mediating activity and a ABCA stabilization activity. The invention further provides methods of using such peptides.

Inventors:
;
Issue Date:
Research Org.:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1176216
Patent Number(s):
7691965
Application Number:
11/014,187
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
DOE Contract Number:  
AC03-76SF00098
Resource Type:
Patent
Resource Relation:
Patent File Date: 2004 Dec 15
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES

Citation Formats

Bielicki, John K., and Natarajan, Pradeep. Helical synthetic peptides that stimulate cellular cholesterol efflux. United States: N. p., 2010. Web.
Bielicki, John K., & Natarajan, Pradeep. Helical synthetic peptides that stimulate cellular cholesterol efflux. United States.
Bielicki, John K., and Natarajan, Pradeep. Tue . "Helical synthetic peptides that stimulate cellular cholesterol efflux". United States. https://www.osti.gov/servlets/purl/1176216.
@article{osti_1176216,
title = {Helical synthetic peptides that stimulate cellular cholesterol efflux},
author = {Bielicki, John K. and Natarajan, Pradeep},
abstractNote = {The present invention provides peptides comprising at least one amphipathic alpha helix and having an cholesterol mediating activity and a ABCA stabilization activity. The invention further provides methods of using such peptides.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 06 00:00:00 EDT 2010},
month = {Tue Apr 06 00:00:00 EDT 2010}
}

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