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Title: System for concentrating and analyzing particles suspended in a fluid

Abstract

Disclosed is a device for separating and concentrating particles suspended in a fluid stream by using dielectrophoresis (DEP) to trap and/or deflect those particles as they migrate through a fluid channel. The method uses fluid channels designed to constrain a liquid flowing through it to uniform electrokinetic flow velocities. This behavior is achieved by connecting deep and shallow sections of channels, with the channel depth varying abruptly along an interface. By careful design of abrupt changes in specific permeability at the interface, an abrupt and spatially uniform change in electrokinetic force can be selected. Because these abrupt interfaces also cause a sharp gradient in applied electric fields, a DEP force also can be established along the interface. Depending on the complex conductivity of the suspended particles and the immersion liquid, the DEP force can controllably complement or oppose the local electrokinetic force transporting the fluid through the channel allowing for manipulation of particles suspended in the transporting liquid.

Inventors:
 [1];  [2];  [3]
  1. Bethesda, MD
  2. Livermore, CA
  3. Danville, CA
Issue Date:
Research Org.:
Sandia Corporation (Livermore, CA)
Sponsoring Org.:
USDOE
OSTI Identifier:
1016678
Patent Number(s):
7931792
Application Number:
US Patent Application 12/208,471
Assignee:
Sandia Corporation (Livermore, CA)
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B03 - SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS B03C - MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION

Citation Formats

Fiechtner, Gregory J, Cummings, Eric B, and Singh, Anup K. System for concentrating and analyzing particles suspended in a fluid. United States: N. p., 2011. Web.
Fiechtner, Gregory J, Cummings, Eric B, & Singh, Anup K. System for concentrating and analyzing particles suspended in a fluid. United States.
Fiechtner, Gregory J, Cummings, Eric B, and Singh, Anup K. Tue . "System for concentrating and analyzing particles suspended in a fluid". United States. https://www.osti.gov/servlets/purl/1016678.
@article{osti_1016678,
title = {System for concentrating and analyzing particles suspended in a fluid},
author = {Fiechtner, Gregory J and Cummings, Eric B and Singh, Anup K},
abstractNote = {Disclosed is a device for separating and concentrating particles suspended in a fluid stream by using dielectrophoresis (DEP) to trap and/or deflect those particles as they migrate through a fluid channel. The method uses fluid channels designed to constrain a liquid flowing through it to uniform electrokinetic flow velocities. This behavior is achieved by connecting deep and shallow sections of channels, with the channel depth varying abruptly along an interface. By careful design of abrupt changes in specific permeability at the interface, an abrupt and spatially uniform change in electrokinetic force can be selected. Because these abrupt interfaces also cause a sharp gradient in applied electric fields, a DEP force also can be established along the interface. Depending on the complex conductivity of the suspended particles and the immersion liquid, the DEP force can controllably complement or oppose the local electrokinetic force transporting the fluid through the channel allowing for manipulation of particles suspended in the transporting liquid.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2011},
month = {4}
}

Patent:

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