Omics-Lethal Human Viruses, Influenza A Experiment IM101

Anderson, Lindsey N.; Eisfeld, Amie J.; Waters, Katrina M.

doi:10.25584/LHVIM101/1661917

Title: Omics-Lethal Human Viruses, Influenza A Experiment IM101

Abstract

The purpose of this experiment was to evaluate the host mouse response to wild-type Influenza A/Vietnam/1203/2004 (H5N1) virus, Influenza A/California/04/2009 (H1N1) virus, and Influenza A/Vietnam/1203/2004 (H5N1; "PB2-627E" and "NS1trunc124") infection. Sample data was obtained from whole mouse lung and processed for transcriptomics expression analysis. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Transcriptomics dataset downloads have a direct relationship to a primary sample submission corresponding to a specific Influenza A virus host infection.

Authors:

;

Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Univ. of Wisconsin, Madison, WI (United States). School of Veterinary Medicine. Pathology Department

Publication Date:: Mon Jan 18 00:00:00 EST 2021

Other Number(s):: IM101
NCBI BioProject: PRJNA287214 (mRNA);NCBI BioProject: PRJNA287215 (miRNA);GEO Series: GSE69945 (mRNA);GEO Series: GSE69944 (miRNA)

DOE Contract Number:: AC05-76RL01830

Research Org.:: Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

Sponsoring Org.:: USDOE Office of Science (SC); National Institute of Allergy and Infectious Diseases (NIAID)

Collaborations:: Modeling Host Responses to Understand Severe Human Virus Infections Program Project

Subject:: 59 BASIC BIOLOGICAL SCIENCES

Keywords:: Virology [edam.topic:0781]; Immune Response [GO:0006955]; Mus musculus [NCBITAXON:10090]; Influenza A virus [NCBITAXON:11320]; Time Sampled Measurement Datasets [IAO:0000584]; Omics [edam.topic:3391]; Gene expression profile data [edam.data:0928]; BioProject Accession Number [NCIT:C175890]; data transformation [SIO:000594]; differential expression analysis [SWO:7000018]; Data Download [schema:DataDownload]

OSTI Identifier:: 1661917

DOI:: https://doi.org/10.25584/LHVIM101/1661917

Citation Formats


                    Anderson, Lindsey N., Eisfeld, Amie J., and Waters, Katrina M. Omics-Lethal Human Viruses, Influenza A Experiment IM101.  United States: N. p., 2021. 
        Web.  doi:10.25584/LHVIM101/1661917.

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                    Anderson, Lindsey N., Eisfeld, Amie J., & Waters, Katrina M. Omics-Lethal Human Viruses, Influenza A Experiment IM101.  United States.  doi:https://doi.org/10.25584/LHVIM101/1661917

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                    Anderson, Lindsey N., Eisfeld, Amie J., and Waters, Katrina M. 2021.  
"Omics-Lethal Human Viruses, Influenza A Experiment IM101".  United States.  doi:https://doi.org/10.25584/LHVIM101/1661917.  https://www.osti.gov/servlets/purl/1661917. Pub date:Mon Jan 18 00:00:00 EST 2021

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@article{osti_1661917,

  title        = {Omics-Lethal Human Viruses, Influenza A Experiment IM101},

  author       = {Anderson, Lindsey N. and Eisfeld, Amie J. and Waters, Katrina M.},

  abstractNote = {The purpose of this experiment was to evaluate the host mouse response to wild-type Influenza A/Vietnam/1203/2004 (H5N1) virus, Influenza A/California/04/2009 (H1N1) virus, and Influenza A/Vietnam/1203/2004 (H5N1; "PB2-627E" and "NS1trunc124") infection. Sample data was obtained from whole mouse lung and processed for transcriptomics expression analysis. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Transcriptomics dataset downloads have a direct relationship to a primary sample submission corresponding to a specific Influenza A virus host infection.},

  doi          = {10.25584/LHVIM101/1661917},

  journal      = {},

  number       = ,

  volume       = ,

  place        = {United States},

  year         = {Mon Jan 18 00:00:00 EST 2021},

  month        = {Mon Jan 18 00:00:00 EST 2021}

}

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DOI: https://doi.org/10.25584/LHVIM101/1661917

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Works referenced in this record:

Hypergraph models of biological networks to identify genes critical to pathogenic viral response
journal, May 2021

Feng, Song; Heath, Emily; Jefferson, Brett
BMC Bioinformatics, Vol. 22, Issue 1
https://doi.org/10.1186/s12859-021-04197-2

Works referencing / citing this record:

PNNL DataHub Project Omics-LHV Profiling of Host Response to Influenza Infection Post-Processed Data Package DOIs
dataset, January 2021

Anderson, Lindsey; McDermott, Jason; Waters, Katrina
Pacific Northwest National Laboratory 2; PNNL
https://doi.org/10.25584/LHVFLU/1773428

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Title: Omics-Lethal Human Viruses, Influenza A Experiment IM101

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Citation Formats

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