Omics-Lethal Human Viruses, Influenza A Experiment ICL105

Anderson, Lindsey N.; Eisfeld, Amie J.; Waters, Katrina M.

doi:10.25584/LHVICL105/1661915

Title: Omics-Lethal Human Viruses, Influenza A Experiment ICL105

Abstract

The purpose of this experiment was to evaluate the host epigenetic response to Influenza A (H5N1) viral infection from human lung adenocarcinoma cells (Calu-3) high throughput sequencing (ChIP-Seq) sample data. Host-associated viral downloads contain one or more primary host-pathogen experimental study metadata design workbooks (supporting metadata only).

Authors:

;

Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Univ. of Wisconsin, Madison, WI (United States). School of Veterinary Medicine. Pathology Department

Publication Date:: 2021-01-18

Other Number(s):: ICL105
NCBI BioProject: PRJNA428999;GEO Series: GSE108881 (ChIP-Seq);SRA: SRP128562

DOE Contract Number:: AC05-76RL01830

Research Org.:: Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

Sponsoring Org.:: USDOE Office of Science (SC); National Institute of Allergy and Infectious Diseases (NIAID)

Collaborations:: Modeling Host Responses to Understand Severe Human Virus Infections Program Project

Subject:: 59 BASIC BIOLOGICAL SCIENCES

Keywords:: Virology [edam.topic:0781]; Immune Response [GO:0006955]; Human virus [NCIT:C14317]; Influenza A virus [NCBITAXON:11320]; Time Sampled Measurement Datasets [IAO:0000584]; ChIP-Seq [EFO:0002692]; Resource Metadata [SIO:001330]

OSTI Identifier:: 1661915

DOI:: https://doi.org/10.25584/LHVICL105/1661915

Citation Formats


                    Anderson, Lindsey N., Eisfeld, Amie J., and Waters, Katrina M. Omics-Lethal Human Viruses, Influenza A Experiment ICL105.  United States: N. p., 2021. 
        Web.  doi:10.25584/LHVICL105/1661915.

Copy to clipboard


                    Anderson, Lindsey N., Eisfeld, Amie J., & Waters, Katrina M. Omics-Lethal Human Viruses, Influenza A Experiment ICL105.  United States.  doi:https://doi.org/10.25584/LHVICL105/1661915

Copy to clipboard


                    Anderson, Lindsey N., Eisfeld, Amie J., and Waters, Katrina M. 2021.  
"Omics-Lethal Human Viruses, Influenza A Experiment ICL105".  United States.  doi:https://doi.org/10.25584/LHVICL105/1661915.  https://www.osti.gov/servlets/purl/1661915. Pub date:Mon Jan 18 00:00:00 EST 2021

Copy to clipboard


                    
@article{osti_1661915,

  title        = {Omics-Lethal Human Viruses, Influenza A Experiment ICL105},

  author       = {Anderson, Lindsey N. and Eisfeld, Amie J. and Waters, Katrina M.},

  abstractNote = {The purpose of this experiment was to evaluate the host epigenetic response to Influenza A (H5N1) viral infection from human lung adenocarcinoma cells (Calu-3) high throughput sequencing (ChIP-Seq) sample data. Host-associated viral downloads contain one or more primary host-pathogen experimental study metadata design workbooks (supporting metadata only).},

  doi          = {10.25584/LHVICL105/1661915},

  journal      = {},

  number       = ,

  volume       = ,

  place        = {United States},

  year         = {2021},

  month        = {1}

}

Copy to clipboard

Dataset:

View Dataset

DOI: https://doi.org/10.25584/LHVICL105/1661915

Save / Share:

Export Metadata

Save to My Library

Works referenced in this record:

MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape
journal, January 2018

Menachery, Vineet D.; Schäfer, Alexandra; Burnum-Johnson, Kristin E.
Proceedings of the National Academy of Sciences, Vol. 115, Issue 5
https://doi.org/10.1073/pnas.1706928115

Works referencing / citing this record:

PNNL DataHub Project Omics-LHV Profiling of Host Response to Influenza Infection Post-Processed Data Package DOIs
dataset, January 2021

Anderson, Lindsey; McDermott, Jason; Waters, Katrina
Pacific Northwest National Laboratory 2; PNNL
https://doi.org/10.25584/LHVFLU/1773428

Similar records in DOE Data Explorer and OSTI.GOV collections:

Omics-Lethal Human Viruses, Influenza A Experiment ICL102

Dataset Anderson, Lindsey N. ; Eisfeld, Amie J. ; Waters, Katrina M.

The purpose of this experiment was to evaluate the human host cellular response to wild-type Influenza A/Anhui/1/2013 (H7N9; "AH1-WT") virus and mutant viruses NS1-L103F/I106M ("AH1-F/M") and partially ferret-adapted ("AH1-691") infection. Sample data was obtained from human lung adenocarcinoma cells (Calu-3) and processed for mRNA, miRNA, proteomics, lipidomics, and metabolomics expression analysis. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Leveraging unique high-resolution Omics capabilities for proteomics, metabolomics, lipidomics, and transcriptomics dataset download each have a direct relationship to a primarymore »« less
Omics-Lethal Human Viruses, Influenza A Experiment ICL103

Dataset Anderson, Lindsey N. ; Eisfeld, Amie J. ; Waters, Katrina M.

The purpose of this experiment was to evaluate the human host response to Influenza A wild-type (H5N1) virus and mutant viruses. Sample data was obtained for human lung adenocarcinoma cell line (Calu-3) infected with WT Influenza A/Vietnam/1203/2004 (H5N1, VN1203) and mutant viruses PB2-K627E and NS1-trunc124 for mRNA, miRNA, proteomics, lipidomics, and metabolomics data analysis. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Leveraging unique high-resolution Omics capabilities for proteomics, metabolomics, lipidomics, and transcriptomics dataset download each have a direct relationshipmore »« less
Omics-Lethal Human Viruses, Influenza A Experiment ICL106

Dataset Anderson, Lindsey N. ; Eisfeld, Amie J. ; Waters, Katrina M.

The purpose of this experiment was to evaluate the human host epigenetic response to Influenza A H5N1 virus and MERS-CoV viral infection from human lung adenocarcinoma cell (Calu-3) high throughput sequencing (MeDIP-Seq) sample data. Host-associated viral downloads contain one or more primary host-pathogen experimental study metadata design workbooks (supporting metadata only).
Omics-Lethal Human Viruses, Influenza A Experiment IM101

Dataset Anderson, Lindsey N. ; Eisfeld, Amie J. ; Waters, Katrina M.

The purpose of this experiment was to evaluate the host mouse response to wild-type Influenza A/Vietnam/1203/2004 (H5N1) virus, Influenza A/California/04/2009 (H1N1) virus, and Influenza A/Vietnam/1203/2004 (H5N1; "PB2-627E" and "NS1trunc124") infection. Sample data was obtained from whole mouse lung and processed for transcriptomics expression analysis. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Transcriptomics dataset downloads have a direct relationship to a primary sample submission corresponding to a specific Influenza A virus host infection.
Omics-Lethal Human Viruses, Influenza A Experiment IM102

Dataset Anderson, Lindsey N. ; Eisfeld, Amie J. ; Waters, Katrina M.

The purpose of this experiment was to evaluate the host response to wild-type Influenza A/Anhui/1/2013 (H7N9; "AH1-WT") virus and mutant viruses NS1-103F/106M ("AH1-F/M") and partially ferret-adapted ("AH1-691") infection. Sample data was obtained from mouse lung tissue and processed for mRNA, miRNA, proteomics, metabolomics, and lipidomics expression analysis. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Leveraging unique high-resolution Omics capabilities for proteomics, metabolomics, lipidomics, and transcriptomics dataset download each have a direct relationship to a primary sample submission corresponding tomore »« less

Similar Records

Title: Omics-Lethal Human Viruses, Influenza A Experiment ICL105

Abstract

Citation Formats

MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape journal, January 2018

PNNL DataHub Project Omics-LHV Profiling of Host Response to Influenza Infection Post-Processed Data Package DOIs dataset, January 2021

MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape
journal, January 2018

PNNL DataHub Project Omics-LHV Profiling of Host Response to Influenza Infection Post-Processed Data Package DOIs
dataset, January 2021