Chromatographic behavior of the enantiomers of 2,2,2-trifluoro-1-(9-anthryl)ethanol on a quinidine-carbamate chiral stational phase

Journal Article · Mon Aug 01 00:00:00 EDT 2005 · Journal of Chromatography A

DOI:https://doi.org/10.1016/j.chroma.2005.07.079· OSTI ID:989569

Asnin, Leonid ^[1]; Gotmar, Gustaf ^[1]; Guiochon, Georges A ^[2]

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1. University of Tennessee, Knoxville (UTK)
2. ORNL

The enantioseparation of 2,2,2-trifluoro-1-(9-anthryl)ethanol on silica-bonded quinidine carbamate was examined under linear chromatographic conditions. The significant impact of nonselective adsorption on the retention was demonstrated. The influences of a polar additive in the mobile phase on the retention, the selectivity and the thermodynamic quantities of the retention were measured. A small effect of the pressure on the selectivity and on the accuracy of the thermodynamic measurements was observed.

• Research Organization: Oak Ridge National Laboratory (ORNL)
• Sponsoring Organization: SC USDOE - Office of Science (SC)
• DOE Contract Number: AC05-00OR22725
• OSTI ID: 989569
• Journal Information: Journal of Chromatography A, Journal Name: Journal of Chromatography A Journal Issue: 2005 Vol. 1091; ISSN 0021-9673
• Country of Publication: United States
• Language: English

Related Subjects

2
2-trifluoro-1-(9-anthryl)ethanol
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
ADSORPTION
ALCOHOLS
CHROMATOGRAPHY
ENANTIOMORPHS
ORGANIC FLUORINE COMPOUNDS
PRESSURE DEPENDENCE
THERMODYNAMICS
chiral stationary phase
enantiomer separation
quinidine carbamate