Compositions of orthogonal glutamyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof
Patent
·
OSTI ID:988159
- San Francisco, CA
- La Jolla, CA
- Cambridge, MA
Compositions and methods of producing components of protein biosynthetic machinery that include glutamyl orthogonal tRNAs, glutamyl orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of glutamyl tRNAs/synthetases are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins using these orthogonal pairs.
- Research Organization:
- The Scripps Research Institute (US)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- FG03-00ER45812
- Assignee:
- The Scripps Research Institute (La Jolla, CA)
- Patent Number(s):
- 7,527,943
- Application Number:
- 10/563,656
- OSTI ID:
- 988159
- Country of Publication:
- United States
- Language:
- English
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