Apparatus and method for concentrating and filtering particles suspended in a fluid

Fiechtner, Gregory J; Cummings, Eric B; Singh, Anup K

Apparatus and method for concentrating and filtering particles suspended in a fluid

Patent · Tue May 19 04:00:00 EDT 2009

OSTI ID:963815

Fiechtner, Gregory J ^[1]; Cummings, Eric B ^[2]; Singh, Anup K ^[3]

Bethesda, MD
Livermore, CA
Danville, CA

Disclosed is a device for separating and concentrating particles suspended in a fluid stream by using dielectrophoresis (DEP) to trap and/or deflect those particles as they migrate through a fluid channel. The method uses fluid channels designed to constrain a liquid flowing through it to uniform electrokinetic flow velocities. This behavior is achieved by connecting deep and shallow sections of channels, with the channel depth varying abruptly along an interface. By careful design of abrupt changes in specific permeability at the interface, an abrupt and spatially uniform change in electrokinetic force can be selected. Because these abrupt interfaces also cause a sharp gradient in applied electric fields, a DEP force also can be established along the interface. Depending on the complex conductivity of the suspended particles and the immersion liquid, the DEP force can controllably complement or oppose the local electrokinetic force transporting the fluid through the channel allowing for manipulation of particles suspended in the transporting liquid.

Research Organization:: Sandia National Laboratories (SNL-CA), Livermore, CA

Sponsoring Organization:: United States Department of Energy

DOE Contract Number:: AC04-94AL85000

Assignee:: Sandia Corporation (Livermore, CA)

Patent Number(s):: 7,534,334

Application Number:: 10/956,446

OSTI ID:: 963815

Country of Publication:: United States

Language:: English

References (10)

An Investigation of High Gradient Dielectrophoretic Filtration Wakeman, R. J.; Butt, G. Chemical Engineering Research and Design, Vol. 81, Issue 8 https://doi.org/10.1205/026387603322482167	journal	September 2003
An image processing and optimal nonlinear filtering technique for particle image velocimetry of microflows Cummings, E. B. Experiments in Fluids, Vol. 29, Issue 7 https://doi.org/10.1007/s003480070006	journal	December 2000
Low-dispersion electrokinetic flows for expanded separation channels in microfluidic systems: Fiechtner, Gregory J.; Cummings, Eric B. Journal of Chromatography A, Vol. 1027, Issue 1-2 https://doi.org/10.1016/j.chroma.2003.08.050	journal	February 2004
Faceted Design of Channels for Low-Dispersion Electrokinetic Flows in Microfluidic Systems Fiechtner, Gregory J.; Cummings, Eric B. Analytical Chemistry, Vol. 75, Issue 18 https://doi.org/10.1021/ac0207776	journal	September 2003
Dielectrophoresis in Microchips Containing Arrays of Insulating Posts: Theoretical and Experimental Results Cummings, Eric B.; Singh, Anup K. Analytical Chemistry, Vol. 75, Issue 18 https://doi.org/10.1021/ac0340612	journal	September 2003
Electrodeless dielectrophoresis for micro total analysis systems Chou, Chia-Fu; Zenhausern, F. IEEE Engineering in Medicine and Biology Magazine, Vol. 22, Issue 6, p. 62-67 https://doi.org/10.1109/MEMB.2003.1266048	journal	November 2003
Dielectrophoretic filter for separation and recovery of biological cells in water Suehiro, J.; Imamura, M. IEEE Transactions on Industry Applications, Vol. 39, Issue 5 https://doi.org/10.1109/TIA.2003.816535	journal	September 2003
Fluorescent Liposome Flow Markers for Microscale Particle-Image Velocimetry Singh, Anup K.; Cummings, Eric B.; Throckmorton, Daniel J. Analytical Chemistry, Vol. 73, Issue 5 https://doi.org/10.1021/ac001159x	journal	March 2001
Insulator-based dielectrophoresis for the selective concentration and separation of live bacteria in water Lapizco-Encinas, Blanca H.; Simmons, Blake A.; Cummings, Eric B. ELECTROPHORESIS, Vol. 25, Issue 1011 https://doi.org/10.1002/elps.200405899	journal	June 2004
Dielectrophoretic Concentration and Separation of Live and Dead Bacteria in an Array of Insulators Lapizco-Encinas, Blanca H.; Simmons, Blake A.; Cummings, Eric B. Analytical Chemistry, Vol. 76, Issue 6 https://doi.org/10.1021/ac034804j	journal	March 2004

Similar Records

System for concentrating and analyzing particles suspended in a fluid

Patent · Tue Apr 26 00:00:00 EDT 2011 · OSTI ID:1016678

Hybrid immersed interface-immersed boundary methods for AC dielectrophoresis

Journal Article · Fri Aug 01 00:00:00 EDT 2014 · Journal of Computational Physics · OSTI ID:22314886

Dielectrophoretic systems without embedded electrodes

Patent · Mon Mar 20 23:00:00 EST 2006 · OSTI ID:908545

Related Subjects

47 OTHER INSTRUMENTATION

Apparatus and method for concentrating and filtering particles suspended in a fluid

Citation Formats

References (10)

Similar Records

Related Subjects