System for concentrating and analyzing particles suspended in a fluid
Abstract
Disclosed is a device for separating and concentrating particles suspended in a fluid stream by using dielectrophoresis (DEP) to trap and/or deflect those particles as they migrate through a fluid channel. The method uses fluid channels designed to constrain a liquid flowing through it to uniform electrokinetic flow velocities. This behavior is achieved by connecting deep and shallow sections of channels, with the channel depth varying abruptly along an interface. By careful design of abrupt changes in specific permeability at the interface, an abrupt and spatially uniform change in electrokinetic force can be selected. Because these abrupt interfaces also cause a sharp gradient in applied electric fields, a DEP force also can be established along the interface. Depending on the complex conductivity of the suspended particles and the immersion liquid, the DEP force can controllably complement or oppose the local electrokinetic force transporting the fluid through the channel allowing for manipulation of particles suspended in the transporting liquid.
- Inventors:
-
- Bethesda, MD
- Livermore, CA
- Danville, CA
- Publication Date:
- Research Org.:
- Sandia Corporation (Livermore, CA)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1016678
- Patent Number(s):
- 7,931,792
- Application Number:
- US Patent Application 12/208,471
- Assignee:
- Sandia Corporation (Livermore, CA)
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
Fiechtner, Gregory J, Cummings, Eric B, and Singh, Anup K. System for concentrating and analyzing particles suspended in a fluid. United States: N. p., 2011.
Web.
Fiechtner, Gregory J, Cummings, Eric B, & Singh, Anup K. System for concentrating and analyzing particles suspended in a fluid. United States.
Fiechtner, Gregory J, Cummings, Eric B, and Singh, Anup K. 2011.
"System for concentrating and analyzing particles suspended in a fluid". United States. https://www.osti.gov/servlets/purl/1016678.
@article{osti_1016678,
title = {System for concentrating and analyzing particles suspended in a fluid},
author = {Fiechtner, Gregory J and Cummings, Eric B and Singh, Anup K},
abstractNote = {Disclosed is a device for separating and concentrating particles suspended in a fluid stream by using dielectrophoresis (DEP) to trap and/or deflect those particles as they migrate through a fluid channel. The method uses fluid channels designed to constrain a liquid flowing through it to uniform electrokinetic flow velocities. This behavior is achieved by connecting deep and shallow sections of channels, with the channel depth varying abruptly along an interface. By careful design of abrupt changes in specific permeability at the interface, an abrupt and spatially uniform change in electrokinetic force can be selected. Because these abrupt interfaces also cause a sharp gradient in applied electric fields, a DEP force also can be established along the interface. Depending on the complex conductivity of the suspended particles and the immersion liquid, the DEP force can controllably complement or oppose the local electrokinetic force transporting the fluid through the channel allowing for manipulation of particles suspended in the transporting liquid.},
doi = {},
url = {https://www.osti.gov/biblio/1016678},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 26 00:00:00 EDT 2011},
month = {Tue Apr 26 00:00:00 EDT 2011}
}