Single Particle X-Ray Diffractive Imaging

Journal Article · Thu Apr 30 00:00:00 EDT 2009 · Nano Lett.8:310-316,2008

OSTI ID:958649

Bogan, M J; Benner, W H; Boutet, S; Rohner, U; Frank, M; Barty, A; Seibert, M M; Maia, F; Marchesini, S; Bajt, S; Woods, B; Riot, V; Hau-Riege, S P; Svenda, M; Marklund, E; Spiller, E; Hajdu, J; Chapman, H N

In nanotechnology, strategies for the creation and manipulation of nanoparticles in the gas phase are critically important for surface modification and substrate-free characterization. Recent coherent diffractive imaging with intense femtosecond X-ray pulses has verified the capability of single-shot imaging of nanoscale objects at suboptical resolutions beyond the radiation-induced damage threshold. By intercepting electrospray-generated particles with a single 15 femtosecond soft-X-ray pulse, we demonstrate diffractive imaging of a nanoscale specimen in free flight for the first time, an important step toward imaging uncrystallized biomolecules.

• Research Organization: SLAC National Accelerator Lab., Menlo Park, CA (United States)
• Sponsoring Organization: USDOE
• DOE Contract Number: AC02-76SF00515
• OSTI ID: 958649
• Report Number(s): SLAC-REPRINT-2009-033; TRN: US201001%%653
• Journal Information: Nano Lett.8:310-316,2008, Vol. 8, Issue 1
• Country of Publication: United States
• Language: English

Related Subjects

77 NANOSCIENCE AND NANOTECHNOLOGY
37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
PARTICLES
X-RAY DIFFRACTION
NANOSTRUCTURES
IMAGES
SOFT X RADIATION
OTHER