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Detection of Electrophilic and Nucleophilic Chemical Agents

Patent ·
OSTI ID:953735

A "real time" method for detecting electrophilic and nucleophilic species generally by employing tunable, precursor sensor materials that mimic the physiological interaction of these agents to form highly florescent berberine-type alkaloids that can be easily and rapidly detected. These novel precursor sensor materials can be tuned for reaction with both electrophilic (chemical species, toxins) and nucleophilic (proteins and other biological molecules) species.

Research Organization:
Sandia National Laboratories (SNL-CA), Livermore, CA
Sponsoring Organization:
United States Department of Energy
DOE Contract Number:
AC04-94AL85000
Assignee:
Sandia Corporation (Livermore, CA)
Patent Number(s):
7,449,579
Application Number:
OSTI ID:
953735
Country of Publication:
United States
Language:
English

References (1)

The fluorescence properties of protoberberine and tetrahydroprotoberberine alkaloids journal January 1976

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