DAnTE: a statistical tool for quantitative analysis of –omics data

Journal Article · Sat May 03 00:00:00 EDT 2008 · Bioinformatics, 24(13):1556-1558

DOI:https://doi.org/10.1093/bioinformatics/btn217· OSTI ID:934883

Polpitiya, Ashoka D.; Qian, Weijun; Jaitly, Navdeep; Petyuk, Vladislav A.; Adkins, Joshua N.; Camp, David G.; Anderson, Gordon A.; Smith, Richard D.

DAnTE (Data Analysis Tool Extension) is a statistical tool designed to address challenges unique to quantitative bottom-up, shotgun proteomics data. This tool has also been demonstrated for microarray data and can easily be extended to other high-throughput data types. DAnTE features selected normalization methods, missing value imputation algorithms, peptide to protein rollup methods, an extensive array of plotting functions, and a comprehensive ANOVA scheme that can handle unbalanced data and random effects. The Graphical User Interface (GUI) is designed to be very intuitive and user friendly.

• Research Organization: Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
• Sponsoring Organization: USDOE
• DOE Contract Number: AC05-76RL01830
• OSTI ID: 934883
• Report Number(s): PNNL-SA-58107; 400412000
• Journal Information: Bioinformatics, 24(13):1556-1558, Vol. 24, Issue 13
• Country of Publication: United States
• Language: English