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Accelerated Gene Evolution and Subfunctionalization in thePseudotetraploid Frog Xenopus Laevis

Journal Article · · BMC Biology
OSTI ID:919498

Ancient whole genome duplications have been implicated in the vertebrate and teleost radiations, and in the emergence of diverse angiosperm lineages, but the evolutionary response to such a perturbation is still poorly understood. The African clawed frog Xenopus laevis experienced a relatively recent tetraploidization {approx} 40 million years ago. Analysis of the considerable amount of EST sequence available for this species together with the genome sequence of the related diploid Xenopus tropicalis provides a unique opportunity to study the genomic response to whole genome duplication.

Research Organization:
Ernest Orlando Lawrence Berkeley NationalLaboratory, Berkeley, CA (US)
Sponsoring Organization:
USDOE Director. Office of Science. Biological andEnvironmental Research
DOE Contract Number:
AC02-05CH11231
OSTI ID:
919498
Report Number(s):
LBNL--59969; BnR: KP1103010
Journal Information:
BMC Biology, Journal Name: BMC Biology Journal Issue: 31 Vol. 5; ISSN 1741-7007
Country of Publication:
United States
Language:
English

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