Multiple-Image Radiography for Human Soft Tissue

Journal Article · Sun Jan 01 04:00:00 EST 2006 · J. Anatomy

DOI:https://doi.org/10.1111/j.1469-7580.2006.00502.x· OSTI ID:914395

Muehleman, C; Li, J; Zhong, Z; Brankov, J; Wernick, M

Conventional radiography only provides a measure of the X-ray attenuation caused by an object; thus, it is insensitive to other inherent informative effects, such as refraction. Furthermore, conventional radiographs are degraded by X-ray scatter that can obscure important details of the object being imaged. The novel X-ray technology diffraction-enhanced imaging (DEI) has recently allowed the visualization of nearly scatter-free images displaying both attenuation and refraction properties. A new method termed multiple-image radiography (MIR) is a significant improvement over DEI, corrects errors in DEI, is more robust to noise and produces an additional image that is entirely new to medical imaging. This new image, which portrays ultra-small-angle X-ray scattering (USAXS) conveys the presence of microstructure in the object, thus differentiating homogeneous tissues from tissues that are irregular on a scale of micrometers. The aim of this study was to examine the use of MIR for evaluation of soft tissue, and in particular to conduct a preliminary investigation of the USAXS image, which has not previously been used in tissue imaging.

• Research Organization: Brookhaven National Laboratory (BNL) National Synchrotron Light Source
• Sponsoring Organization: Doe - Office Of Science
• DOE Contract Number: AC02-98CH10886
• OSTI ID: 914395
• Report Number(s): BNL--78963-2007-JA
• Journal Information: J. Anatomy, Journal Name: J. Anatomy Vol. 208; ISSN 0021-8782; ISSN JOANAY
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMAL TISSUES
AUGMENTATION
BIOMEDICAL RADIOGRAPHY
IMAGES
REFRACTION
SMALL ANGLE SCATTERING
X-RAY DIFFRACTION
national synchrotron light source