Fermentation process using specific oxygen uptake rates as a process control
Patent
·
OSTI ID:909704
Specific oxygen uptake (OUR) is used as a process control parameter in fermentation processes. OUR is determined during at least the production phase of a fermentation process, and process parameters are adjusted to maintain the OUR within desired ranges. The invention is particularly applicable when the fermentation is conducted using a microorganism having a natural PDC pathway that has been disrupted so that it no longer functions. Microorganisms of this sort often produce poorly under strictly anaerobic conditions. Microaeration controlled by monitoring OUR allows the performance of the microorganism to be optimized.
- Research Organization:
- Cargill Dow Polymers LLC
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- FC36-00GO10598
- Assignee:
- NatureWorks LLC (Minnetonka, MN)
- Patent Number(s):
- 7,232,664
- Application Number:
- 10/449,911
- OSTI ID:
- 909704
- Country of Publication:
- United States
- Language:
- English
Replacement of a Metabolic Pathway for Large-Scale Production of Lactic Acid from Engineered Yeasts
|
journal | September 1999 |
Efficient Homolactic Fermentation by Kluyveromyces lactis Strains Defective in Pyruvate Utilization and Transformed with the Heterologous LDH Gene
|
journal | December 2001 |
Development of metabolically engineered Saccharomyces cerevisiae cells for the production of lactic acid
|
journal | May 1995 |
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