Skip to main content
OSTI.GOVU.S. Department of Energy Office of Scientific and Technical Information
U.S. Department of Energy
Office of Scientific and Technical Information
 

Fermentation process using specific oxygen uptake rates as a process control

Patent ·
OSTI ID:909704
; ;
Specific oxygen uptake (OUR) is used as a process control parameter in fermentation processes. OUR is determined during at least the production phase of a fermentation process, and process parameters are adjusted to maintain the OUR within desired ranges. The invention is particularly applicable when the fermentation is conducted using a microorganism having a natural PDC pathway that has been disrupted so that it no longer functions. Microorganisms of this sort often produce poorly under strictly anaerobic conditions. Microaeration controlled by monitoring OUR allows the performance of the microorganism to be optimized.
Research Organization:
Cargill Dow Polymers LLC
Sponsoring Organization:
United States Department of Energy
DOE Contract Number:
FC36-00GO10598
Assignee:
NatureWorks LLC (Minnetonka, MN)
Patent Number(s):
7,232,664
Application Number:
10/449,911
OSTI ID:
909704
Country of Publication:
United States
Language:
English

References (3)

Efficient Homolactic Fermentation by Kluyveromyces lactis Strains Defective in Pyruvate Utilization and Transformed with the Heterologous LDH Gene journal December 2001
Development of metabolically engineered Saccharomyces cerevisiae cells for the production of lactic acid journal May 1995
Replacement of a Metabolic Pathway for Large-Scale Production of Lactic Acid from Engineered Yeasts journal September 1999

Similar Records

Fermentation process using specific oxygen uptake rates as a process control
Patent · Tue Sep 09 00:00:00 EDT 2014 · OSTI ID:1157563
Fermentation process using specific oxygen uptake rates as a process control
Patent · Tue May 10 00:00:00 EDT 2011 · OSTI ID:1021878
Fermentation process using specific oxygen uptake rates as a process control
Patent · Tue Aug 30 00:00:00 EDT 2016 · OSTI ID:1312649

Related Subjects

59 BASIC BIOLOGICAL SCIENCES