Fermentation process using specific oxygen uptake rates as a process control
Patent
·
OSTI ID:1312649
Specific oxygen uptake (OUR) is used as a process control parameter in fermentation processes. OUR is determined during at least the production phase of a fermentation process, and process parameters are adjusted to maintain the OUR within desired ranges. The invention is particularly applicable when the fermentation is conducted using a microorganism having a natural PDC pathway that has been disrupted so that it no longer functions. Microorganisms of this sort often produce poorly under strictly anaerobic conditions. Microaeration controlled by monitoring OUR allows the performance of the microorganism to be optimized.
- Research Organization:
- Cargill Incorporated, Wayzata, MN (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- FC36-00GO10598
- Assignee:
- Cargill Incorporated (Wayzata, MN)
- Patent Number(s):
- 9,428,776
- Application Number:
- 14/479,309
- OSTI ID:
- 1312649
- Country of Publication:
- United States
- Language:
- English
Efficient Homolactic Fermentation by Kluyveromyces lactis Strains Defective in Pyruvate Utilization and Transformed with the Heterologous LDH Gene
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journal | December 2001 |
Effect of benzoic acid on metabolic fluxes in yeasts: A continuous-culture study on the regulation of respiration and alcoholic fermentation
|
journal | July 1992 |
Development of metabolically engineered Saccharomyces cerevisiae cells for the production of lactic acid
|
journal | May 1995 |
Large scale production of cyclohexanone monooxygenase from Escherichia coli TOP10 pQR239
|
journal | February 2001 |
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