FTIR Spectroscopy for Bacterial Spore Identification and Classification
The ability to distinguish endospores from each other, from vegetative cells, and from background particles has been demonstrated by PNNL and several other laboratories using various analytical techniques such as MALDI and SIMS. Recent studies at PNNL using Fourier transform Infrared (FTIR) spectroscopy combined with statistical analysis have shown the ability to characterize and discriminate bacterial spores and vegetative bacteria from each other, as well as from background interferents. In some cases it is even possible to determine the taxonomical identity of the species using FTIR. This effort has now grown to include multiple species of bacterial endospores, vegetative cells, and background materials. The present work reports on advances in being able to use FTIR, or IR in combination with other techniques, for rapid and reliable discrimination.
- Research Organization:
- Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC05-76RL01830
- OSTI ID:
- 901188
- Report Number(s):
- PNNL-SA-51859; TRN: US200713%%87
- Resource Relation:
- Conference: Chemical and Biological Sensors for Industrial and Environmental Monitoring II. Proceedings- SPIE the International Society for Optical Engineering, 6378:63780P, (10 pages)
- Country of Publication:
- United States
- Language:
- English
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