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Verification of the HRQAR two-dimensional approach for NCT microdosimetry

Journal Article · · Transactions of the American Nuclear Society
OSTI ID:89056
 [1]; ;
  1. Massachusetts Institute of Technology, Cambridge, MA (United States)
A unique approach to the microdosimetry of neutron capture therapy (NCT), which combines the high-resolution quantitative autoradiography (HRQAR) technique, and two-dimensional (2-D) Monte Carlo methods, has been developed by our group. Using this approach, actual cell morphology (ie., cell nuclei and cytoplasm structures) and microdistribution of the capture element (e.g., {sup 10}B) can be obtained; therefore, microdosimetry can be carried out without making any assumptions regarding either cell architecture or {sup 10}B distribution. This paper shows that results obtained by this 2-D approach are equivalent to the {open_quotes}traditional{close_quotes} 3-D approach.
OSTI ID:
89056
Report Number(s):
CONF-941102--
Journal Information:
Transactions of the American Nuclear Society, Journal Name: Transactions of the American Nuclear Society Vol. 71; ISSN 0003-018X; ISSN TANSAO
Country of Publication:
United States
Language:
English

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