NMR in rotating magnetic fields: Magic angle field spinning

Journal Article · Fri Sep 10 04:00:00 EDT 2004 · Magnetic Resonance Imaging

OSTI ID:887191

Sakellariou, D; Meriles, C; Martin, R; Pines, A

Magic angle sample spinning has been one of the cornerstones in high-resolution solid state NMR. Spinning frequencies nowadays have increased by at least one order of magnitude over the ones used in the first experiments and the technique has gained tremendous popularity. It is currently a routine procedure in solid-state NMR, high-resolution liquid-state NMR and solid-state MRI. The technique enhances the spectral resolution by averaging away rank 2 anisotropic spin interactions thereby producing isotropic-like spectra with resolved chemical shifts and scalar couplings. Andrew proposed that it should be possible to induce similar effects in a static sample if the direction of the magnetic field is varied, e.g., magic-angle rotation of the B0 field (B0-MAS) and this has been recently demonstrated using electromagnetic field rotation. Here we discuss on the possibilities to perform field rotation using alternative hardware, together with spectroscopic methods to recover isotropic resolution even in cases where the field is not rotating at the magic angle. Extension to higher magnetic fields would be beneficial in situations where the physical manipulation of the sample is inconvenient or impossible. Such situations occur often in materials or biomedical samples where ''ex-situ'' NMR spectroscopy and imaging analysis is needed.

• Research Organization: Ernest Orlando Lawrence Berkeley NationalLaboratory, Berkeley, CA (US)
• Sponsoring Organization: USDOE Director. Office of Science. Office of Basic EnergySciences
• DOE Contract Number: AC02-05CH11231
• OSTI ID: 887191
• Report Number(s): LBNL--56821; BnR: KC0203010
• Journal Information: Magnetic Resonance Imaging, Journal Name: Magnetic Resonance Imaging Vol. 23; ISSN 0730-725X; ISSN MRIMDQ
• Country of Publication: United States
• Language: English

Related Subjects

36 MATERIALS SCIENCE
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
CHEMICAL SHIFT
ELECTROMAGNETIC FIELDS
MAGNETIC FIELDS
NMR magic angle field spinning rotating magnetic fieldsMAS
RESOLUTION
ROTATION
SCALARS
SPECTRA
SPECTROSCOPY
SPIN