Kinetic Steering of Quinol Oxidation by ‘Proton Stripping’ at the Cytochrome bc1 Complex Qo Site
Conference
·
OSTI ID:877040
The cyt bc1 complex and the related cyt b6f and bc-type complexes are key components of chemiosmotic energy conversion in mitochondria, chloroplasts and many bacteria. These complexes oxidize a range of different quinol or hydroquinone (QH2) molecules—ubihydroquinone (UQH2) in the case of mitochondria and many bacteria, plastohydroquinone (PQH2) in chloroplasts and cyanobacteria, and menahydroquinone in many bacteria—to the corresponding quinone (Q), and reduce a range of soluble electron carriers, e.g. cyt c in purple bacteria and mitochondria, plastocyanin in chloroplasts. The redox reactions are coupled to the translocation of protons across the energetic membrane to store energy in an electrochemical proton gradient, or proton motive force (pmf) which drives ATP synthesis.
- Research Organization:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (US), Environmental Molecular Sciences Laboratory (EMSL)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC05-76RL01830
- OSTI ID:
- 877040
- Report Number(s):
- PNNL-SA-45299; 2358a; KP1704020
- Country of Publication:
- United States
- Language:
- English
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OSTI ID:877039
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Journal Article
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· Biochemistry
·
OSTI ID:15008816
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· Journal of Biological Chemistry, 281(50):38459-38465
·
OSTI ID:897679
Related Subjects
59 BASIC BIOLOGICAL SCIENCES
72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS
BACTERIA
BENZOQUINONES
CHLOROPLASTS
CYANOBACTERIA
CYTOCHROMES
ELECTRONS
ENERGY CONVERSION
Environmental Molecular Sciences Laboratory
KINETICS
MEMBRANES
MITOCHONDRIA
OXIDATION
PHOTOSYNTHESIS
PROTONS
REDOX REACTIONS
SYNTHESIS
TRANSLOCATION
72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS
BACTERIA
BENZOQUINONES
CHLOROPLASTS
CYANOBACTERIA
CYTOCHROMES
ELECTRONS
ENERGY CONVERSION
Environmental Molecular Sciences Laboratory
KINETICS
MEMBRANES
MITOCHONDRIA
OXIDATION
PHOTOSYNTHESIS
PROTONS
REDOX REACTIONS
SYNTHESIS
TRANSLOCATION