A Biomimetic Approach to Discrimination Between Sequential and Concerted Models for the Oxidation of Ubiquinol at the Qo site of the Cyt bc1 Complex
Conference
·
OSTI ID:877038
The cytochrome bc complexes function as quinol:cytochrome c oxidoreductases in the energy conserving membranes of nearly all organisms, where they couple the oxidation of a quinol substrate (QH2) to the pumping of protons across the bioenergetic membrane, resulting in the establishment of a proton motive force, which is used to drive the (C)F0/(C)F1 ATP synthase (Trumpower and Gennis 1994). Among the variety of biological quinols characterized, ubiquinol is the substrate used by most bc-type complexes, and its reactions are of great interest concerning diseases related to oxidative stress and the fundamentals of biological energy transduction.
- Research Organization:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (US), Environmental Molecular Sciences Laboratory (EMSL)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC05-76RL01830
- OSTI ID:
- 877038
- Report Number(s):
- PNNL-SA-45294; 2358a; KP1704020
- Country of Publication:
- United States
- Language:
- English
Similar Records
Sequential Two-Electron Oxidation of Ubiquinol by the Cytochrome bc1 Complex
THE RESPIRATORY SUBSTRATE RHODOQUINOL INDUCES Q-CYCLE BYPASS REACTIONS IN THE YEAST CYTOCHROME bc1 COMPLEX - MECHANISTIC AND PHYSIOLOGICAL IMPLICATIONS
Reaction Intermediates of Quinol Oxidation in a Photoactivatable System that Mimics Electron Transfer in the Cytochrome bc1 Complex
Conference
·
Fri May 13 00:00:00 EDT 2005
·
OSTI ID:877039
THE RESPIRATORY SUBSTRATE RHODOQUINOL INDUCES Q-CYCLE BYPASS REACTIONS IN THE YEAST CYTOCHROME bc1 COMPLEX - MECHANISTIC AND PHYSIOLOGICAL IMPLICATIONS
Journal Article
·
Mon Aug 08 00:00:00 EDT 2005
· Journal of Biological Chemistry
·
OSTI ID:876945
Reaction Intermediates of Quinol Oxidation in a Photoactivatable System that Mimics Electron Transfer in the Cytochrome bc1 Complex
Journal Article
·
Tue Mar 29 23:00:00 EST 2005
· Journal of the American Chemical Society
·
OSTI ID:15015964