Dual mode stereotactic localization method and application

Patent · Mon Dec 31 23:00:00 EST 2001

OSTI ID:874440

Keppel, Cynthia E ^[1]; Barbosa, Fernando Jorge ^[2]; Majewski, Stanislaw ^[3]

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1. Norfolk, VA
2. Newport News, VA
3. Grafton, VA

The invention described herein combines the structural digital X-ray image provided by conventional stereotactic core biopsy instruments with the additional functional metabolic gamma imaging obtained with a dedicated compact gamma imaging mini-camera. Before the procedure, the patient is injected with an appropriate radiopharmaceutical. The radiopharmaceutical uptake distribution within the breast under compression in a conventional examination table expressed by the intensity of gamma emissions is obtained for comparison (co-registration) with the digital mammography (X-ray) image. This dual modality mode of operation greatly increases the functionality of existing stereotactic biopsy devices by yielding a much smaller number of false positives than would be produced using X-ray images alone. The ability to obtain both the X-ray mammographic image and the nuclear-based medicine gamma image using a single device is made possible largely through the use of a novel, small and movable gamma imaging camera that permits its incorporation into the same table or system as that currently utilized to obtain X-ray based mammographic images for localization of lesions.

• Research Organization: SOUTHEASTERN UNIV RESCH ASSN
• DOE Contract Number: AC05-84ER40150
• Assignee: Southeastern Universities Research Assn., Inc. (Newport News, VA)
• Patent Number(s): US 6389098
• OSTI ID: 874440
• Country of Publication: United States
• Language: English

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ability
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combines
compact
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core
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digital
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dual
emissions
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