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Title: Dual mode stereotactic localization method and application

Abstract

The invention described herein combines the structural digital X-ray image provided by conventional stereotactic core biopsy instruments with the additional functional metabolic gamma imaging obtained with a dedicated compact gamma imaging mini-camera. Before the procedure, the patient is injected with an appropriate radiopharmaceutical. The radiopharmaceutical uptake distribution within the breast under compression in a conventional examination table expressed by the intensity of gamma emissions is obtained for comparison (co-registration) with the digital mammography (X-ray) image. This dual modality mode of operation greatly increases the functionality of existing stereotactic biopsy devices by yielding a much smaller number of false positives than would be produced using X-ray images alone. The ability to obtain both the X-ray mammographic image and the nuclear-based medicine gamma image using a single device is made possible largely through the use of a novel, small and movable gamma imaging camera that permits its incorporation into the same table or system as that currently utilized to obtain X-ray based mammographic images for localization of lesions.

Inventors:
 [1];  [2];  [3]
  1. (Norfolk, VA)
  2. (Newport News, VA)
  3. (Grafton, VA)
Publication Date:
Research Org.:
SOUTHEASTERN UNIV RESCH ASSN
OSTI Identifier:
874440
Patent Number(s):
US 6389098
Assignee:
Southeastern Universities Research Assn., Inc. (Newport News, VA) TJNAF
DOE Contract Number:  
AC05-84ER40150
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
dual; mode; stereotactic; localization; method; application; described; combines; structural; digital; x-ray; image; provided; conventional; core; biopsy; instruments; additional; functional; metabolic; gamma; imaging; obtained; dedicated; compact; mini-camera; procedure; patient; injected; appropriate; radiopharmaceutical; uptake; distribution; breast; compression; examination; expressed; intensity; emissions; comparison; co-registration; mammography; modality; operation; greatly; increases; functionality; existing; devices; yielding; false; positives; produced; images; ability; obtain; mammographic; nuclear-based; medicine; single; device; novel; movable; camera; permits; incorporation; currently; utilized; based; lesions; x-ray image; /378/250/

Citation Formats

Keppel, Cynthia E., Barbosa, Fernando Jorge, and Majewski, Stanislaw. Dual mode stereotactic localization method and application. United States: N. p., 2002. Web.
Keppel, Cynthia E., Barbosa, Fernando Jorge, & Majewski, Stanislaw. Dual mode stereotactic localization method and application. United States.
Keppel, Cynthia E., Barbosa, Fernando Jorge, and Majewski, Stanislaw. Tue . "Dual mode stereotactic localization method and application". United States. https://www.osti.gov/servlets/purl/874440.
@article{osti_874440,
title = {Dual mode stereotactic localization method and application},
author = {Keppel, Cynthia E. and Barbosa, Fernando Jorge and Majewski, Stanislaw},
abstractNote = {The invention described herein combines the structural digital X-ray image provided by conventional stereotactic core biopsy instruments with the additional functional metabolic gamma imaging obtained with a dedicated compact gamma imaging mini-camera. Before the procedure, the patient is injected with an appropriate radiopharmaceutical. The radiopharmaceutical uptake distribution within the breast under compression in a conventional examination table expressed by the intensity of gamma emissions is obtained for comparison (co-registration) with the digital mammography (X-ray) image. This dual modality mode of operation greatly increases the functionality of existing stereotactic biopsy devices by yielding a much smaller number of false positives than would be produced using X-ray images alone. The ability to obtain both the X-ray mammographic image and the nuclear-based medicine gamma image using a single device is made possible largely through the use of a novel, small and movable gamma imaging camera that permits its incorporation into the same table or system as that currently utilized to obtain X-ray based mammographic images for localization of lesions.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2002},
month = {1}
}

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