Method for determining properties of red blood cells

Patent · 31 December 2000

OSTI ID:873551

Gourley, Paul L ^[1]

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1. Albuquerque, NM

A method for quantifying the concentration of hemoglobin in a cell, and indicia of anemia, comprises determining the wavelength of the longitudinal mode of a liquid in a laser microcavity; determining the wavelength of the fundamental transverse mode of a red blood cell in the liquid in the laser microcavity; and determining if the cell is anemic from the difference between the wavelength of the longitudinal mode and the fundamental transverse mode. In addition to measuring hemoglobin, the invention includes a method using intracavity laser spectroscopy to measure the change in spectra as a function of time for measuring the influx of water into a red blood cell and the cell's subsequent rupture.

• Research Organization: SANDIA CORP
• DOE Contract Number: AC04-94AL85000
• Assignee: Sandia Corporation (Albuquerque, NM)
• Patent Number(s): US 6187592
• OSTI ID: 873551
• Country of Publication: United States
• Language: English

Related Subjects

/436/356/
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anemia
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blood
blood cell
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cell
cells
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concentration
determining
determining properties
difference
function
fundamental
hemoglobin
indicia
influx
intracavity
laser
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liquid
longitudinal
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measure
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method
microcavity
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spectra
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subsequent
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transverse
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water
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