Recombinant lactobacillus for fermentation of xylose to lactic acid and lactate

Picataggio, Stephen K; Zhang, Min; Franden, Mary Ann; Mc Millan, James D; Finkelstein, Mark

Recombinant lactobacillus for fermentation of xylose to lactic acid and lactate

Patent · Wed Dec 31 23:00:00 EST 1997

OSTI ID:871796

Picataggio, Stephen K ^[1]; Zhang, Min ^[2]; Franden, Mary Ann ^[3]; Mc Millan, James D ^[4]; Finkelstein, Mark ^[5]

Golden, CO
Lakewood, CO
Littleton, CO
Boulder, CO
Fort Collins, CO

A recombinant Lactobacillus MONT4 is provided which has been genetically engineered with xylose isomerase and xylulokinase genes from Lactobacillus pentosus to impart to the Lactobacillus MONT4 the ability to ferment lignocellulosic biomass containing xylose to lactic acid.

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Research Organization:: Midwest Research Institute

DOE Contract Number:: AC36-83CH10093

Assignee:: Midwest Research Institute (Kansas City, MI)

Patent Number(s):: US 5798237

OSTI ID:: 871796

Country of Publication:: United States

Language:: English

References (14)

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Molecular cloning in Lactobacillus helveticus by plasmid pSA3::pVA797 co-integrate formation and conjugal transfer Thompson, Keith; Collins, Martin Applied Microbiology and Biotechnology, Vol. 35, Issue 3 https://doi.org/10.1007/BF00172722	journal	June 1991
Identification of Thermobacteria and Homofermentative, Thermophilic, Pentose-utilizing Lactobacilli from High Temperature Fermenting Grape Musts Barre, P. Journal of Applied Bacteriology, Vol. 44, Issue 1 https://doi.org/10.1111/j.1365-2672.1978.tb00783.x	journal	February 1978
Structural and functional analysis of two cryptic plasmids from Lactobacillus pentosus MD353 and Lactobacillus plantarum ATCC 8014 Leer, Rob J.; van Luijk, Nicole; Posno, Mark Molecular and General Genetics MGG, Vol. 234, Issue 2 https://doi.org/10.1007/BF00283847	journal	August 1992
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Bradford, Marion M. Analytical Biochemistry, Vol. 72, Issue 1-2 https://doi.org/10.1016/0003-2697(76)90527-3	journal	May 1976
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Incompatibility of Lactobacillus Vectors with Replicons Derived from Small Cryptic Lactobacillus Plasmids and Segregational Instability of the Introduced Vectors Posno, M.; Leer, R. J.; van Luijk, N. Applied and Environmental Microbiology, Vol. 57, Issue 6 https://doi.org/10.1128/AEM.57.6.1822-1828.1991	journal	January 1991
Identification and sequence analysis of the Bacillus subtilis W23 xylR gene and xyl operator Kreuzer, P.; Gärtner, D.; Allmansberger, R. Journal of Bacteriology, Vol. 171, Issue 7 https://doi.org/10.1128/JB.171.7.3840-3845.1989	journal	July 1989
Ethanol tolerance and carbohydrate metabolism in lactobacilli Gold, R. Shane; Meagher, M. M.; Hutkins, R. Journal of Industrial Microbiology, Vol. 10, Issue 1 https://doi.org/10.1007/BF01583633	journal	July 1992
Promotor analysis and transcriptional regulation of Lactobacillus pentosus genes involved in xylose catabolism Lokman, B. Christien; Leer, Rob J.; van Sorge, Renée Molecular and General Genetics MGG, Vol. 245, Issue 1 https://doi.org/10.1007/BF00279757	journal	January 1994
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Organization and characterization of three genes involved in d-xylose catabolism in Lactobacillus pentosus Lokman, B. Christien; van Santen, Pieter; Verdoes, Jan C. Molecular and General Genetics MGG, Vol. 230, Issue 1-2 https://doi.org/10.1007/BF00290664	journal	November 1991
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Related Subjects

/435/
ability
acid
biomass
containing
engineered
ferment
fermentation
genes
genetically
genetically engineered
impart
isomerase
lactate
lactic
lactic acid
lactobacillus
lignocellulosic
lignocellulosic biomass
mont4
pentosus
provided
recombinant
recombinant lactobacillus
xylose
xylose isomerase
xylulokinase

Recombinant lactobacillus for fermentation of xylose to lactic acid and lactate

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References (14)

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