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Title: Nuclear magnetic resonance contrast agents

Abstract

A family of contrast agents for use in magnetic resonance imaging and a method of enhancing the contrast of magnetic resonance images of an object by incorporating a contrast agent of this invention into the object prior to forming the images or during formation of the images. A contrast agent of this invention is a paramagnetic lanthanide hexaazamacrocyclic molecule, where a basic example has the formula LnC.sub.16 H.sub.14 N.sub.6. Important applications of the invention are in medical diagnosis, treatment, and research, where images of portions of a human body are formed by means of magnetic resonance techniques.

Inventors:
 [1];  [1];  [1];  [1]
  1. (Los Alamos, NM)
Publication Date:
Research Org.:
Los Alamos National Laboratory (LANL), Los Alamos, NM
OSTI Identifier:
871291
Patent Number(s):
US 5702683
Assignee:
United States of America as represented by United States (Washington, DC) LANL
DOE Contract Number:  
W-7405-ENG-36
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
nuclear; magnetic; resonance; contrast; agents; family; imaging; method; enhancing; images; incorporating; agent; prior; forming; formation; paramagnetic; lanthanide; hexaazamacrocyclic; molecule; basic; example; formula; lnc; 16; 14; applications; medical; diagnosis; treatment; portions; human; formed; means; techniques; resonance imaging; magnetic resonance; nuclear magnetic; resonance techniques; medical diagnosis; contrast agents; contrast agent; /424/436/999/

Citation Formats

Smith, Paul H., Brainard, James R., Jarvinen, Gordon D., and Ryan, Robert R. Nuclear magnetic resonance contrast agents. United States: N. p., 1997. Web.
Smith, Paul H., Brainard, James R., Jarvinen, Gordon D., & Ryan, Robert R. Nuclear magnetic resonance contrast agents. United States.
Smith, Paul H., Brainard, James R., Jarvinen, Gordon D., and Ryan, Robert R. Wed . "Nuclear magnetic resonance contrast agents". United States. https://www.osti.gov/servlets/purl/871291.
@article{osti_871291,
title = {Nuclear magnetic resonance contrast agents},
author = {Smith, Paul H. and Brainard, James R. and Jarvinen, Gordon D. and Ryan, Robert R.},
abstractNote = {A family of contrast agents for use in magnetic resonance imaging and a method of enhancing the contrast of magnetic resonance images of an object by incorporating a contrast agent of this invention into the object prior to forming the images or during formation of the images. A contrast agent of this invention is a paramagnetic lanthanide hexaazamacrocyclic molecule, where a basic example has the formula LnC.sub.16 H.sub.14 N.sub.6. Important applications of the invention are in medical diagnosis, treatment, and research, where images of portions of a human body are formed by means of magnetic resonance techniques.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Wed Jan 01 00:00:00 EST 1997},
month = {Wed Jan 01 00:00:00 EST 1997}
}

Patent:

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