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Nuclear magnetic resonance contrast agents

Patent ·
OSTI ID:563675

A family of contrast agents for use in magnetic resonance imaging and a method of enhancing the contrast of magnetic resonance images of an object by incorporating a contrast agent of this invention into the object prior to forming the images or during formation of the images. A contrast agent of this invention is a paramagnetic lanthanide hexaazamacrocyclic molecule, where a basic example has the formula LnC{sub 16}H{sub 14}N{sub 6}. Important applications of the invention are in medical diagnosis, treatment, and research, where images of portions of a human body are formed by means of magnetic resonance techniques. 10 figs.

Research Organization:
University of California
Sponsoring Organization:
USDOE, Washington, DC (United States)
DOE Contract Number:
W-7405-ENG-36
Assignee:
Dept. of Energy, Washington, DC (United States)
Patent Number(s):
US 5,702,683/A/
Application Number:
PAN: 7-643,092
OSTI ID:
563675
Country of Publication:
United States
Language:
English

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