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Title: Nuclear magnetic resonance contrast agents

Abstract

A family of contrast agents for use in magnetic resonance imaging and a method of enhancing the contrast of magnetic resonance images of an object by incorporating a contrast agent of this invention into the object prior to forming the images or during formation of the images. A contrast agent of this invention is a paramagnetic lanthanide hexaazamacrocyclic molecule, where a basic example has the formula LnC{sub 16}H{sub 14}N{sub 6}. Important applications of the invention are in medical diagnosis, treatment, and research, where images of portions of a human body are formed by means of magnetic resonance techniques. 10 figs.

Inventors:
; ; ;
Publication Date:
Research Org.:
University of California
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
563675
Patent Number(s):
US 5,702,683/A/
Application Number:
PAN: 7-643,092
Assignee:
Dept. of Energy, Washington, DC (United States) PTO; SCA: 550600; PA: EDB-98:016273; SN: 98001896299
DOE Contract Number:  
W-7405-ENG-36
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 30 Dec 1997
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; NMR IMAGING; CONTRAST MEDIA; NUCLEAR MAGNETIC RESONANCE; IMAGE PROCESSING; NUCLEAR MEDICINE

Citation Formats

Smith, P.H., Brainard, J.R., Jarvinen, G.D., and Ryan, R.R. Nuclear magnetic resonance contrast agents. United States: N. p., 1997. Web.
Smith, P.H., Brainard, J.R., Jarvinen, G.D., & Ryan, R.R. Nuclear magnetic resonance contrast agents. United States.
Smith, P.H., Brainard, J.R., Jarvinen, G.D., and Ryan, R.R. Tue . "Nuclear magnetic resonance contrast agents". United States.
@article{osti_563675,
title = {Nuclear magnetic resonance contrast agents},
author = {Smith, P.H. and Brainard, J.R. and Jarvinen, G.D. and Ryan, R.R.},
abstractNote = {A family of contrast agents for use in magnetic resonance imaging and a method of enhancing the contrast of magnetic resonance images of an object by incorporating a contrast agent of this invention into the object prior to forming the images or during formation of the images. A contrast agent of this invention is a paramagnetic lanthanide hexaazamacrocyclic molecule, where a basic example has the formula LnC{sub 16}H{sub 14}N{sub 6}. Important applications of the invention are in medical diagnosis, treatment, and research, where images of portions of a human body are formed by means of magnetic resonance techniques. 10 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Dec 30 00:00:00 EST 1997},
month = {Tue Dec 30 00:00:00 EST 1997}
}