Method for synthesizing peptides with saccharide linked enzyme polymer conjugates

Callstrom, Matthew R; Bednarski, Mark D; Gruber, Patrick R

Method for synthesizing peptides with saccharide linked enzyme polymer conjugates

Patent · Tue Dec 31 23:00:00 EST 1996

OSTI ID:871005

Callstrom, Matthew R ^[1]; Bednarski, Mark D ^[2]; Gruber, Patrick R ^[3]

Columbus, OH
Berkeley, CA
St. Paul, MN

A method is disclosed for synthesizing peptides using water soluble enzyme polymer conjugates. The method comprises catalyzing the peptide synthesis with enzyme which has been covalently bonded to a polymer through at least three linkers which linkers have three or more hydroxyl groups. The enzyme is conjugated at lysines or arginines.

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA

DOE Contract Number:: AC03-76SF00098

Assignee:: Cargill, Incorporated (Minneapolis, MN)

Patent Number(s):: US 5639633

OSTI ID:: 871005

Country of Publication:: United States

Language:: English

References (57)

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/435/
arginines
bonded
catalyzing
comprises
conjugated
conjugates
covalently
covalently bonded
disclosed
enzyme
enzyme polymer
hydroxyl
linked
linkers
lysines
method
method comprise
method comprises
peptide
peptides
polymer
polymer conjugates
saccharide
soluble
synthesis
synthesizing
synthesizing peptides
water
water soluble

Method for synthesizing peptides with saccharide linked enzyme polymer conjugates

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