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Title: Method for synthesizing peptides with saccharide linked enzyme polymer conjugates

Abstract

A method is disclosed for synthesizing peptides using water soluble enzyme polymer conjugates. The method comprises catalyzing the peptide synthesis with enzyme which has been covalently bonded to a polymer through at least three linkers which linkers have three or more hydroxyl groups. The enzyme is conjugated at lysines or arginines.

Inventors:
 [1];  [2];  [3]
  1. (Columbus, OH)
  2. (Berkeley, CA)
  3. (St. Paul, MN)
Publication Date:
Research Org.:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA
OSTI Identifier:
871005
Patent Number(s):
US 5639633
Assignee:
Cargill, Incorporated (Minneapolis, MN) LBNL
DOE Contract Number:  
AC03-76SF00098
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
method; synthesizing; peptides; saccharide; linked; enzyme; polymer; conjugates; disclosed; water; soluble; comprises; catalyzing; peptide; synthesis; covalently; bonded; linkers; hydroxyl; conjugated; lysines; arginines; water soluble; method comprises; covalently bonded; polymer conjugates; method comprise; synthesizing peptides; enzyme polymer; /435/

Citation Formats

Callstrom, Matthew R., Bednarski, Mark D., and Gruber, Patrick R. Method for synthesizing peptides with saccharide linked enzyme polymer conjugates. United States: N. p., 1997. Web.
Callstrom, Matthew R., Bednarski, Mark D., & Gruber, Patrick R. Method for synthesizing peptides with saccharide linked enzyme polymer conjugates. United States.
Callstrom, Matthew R., Bednarski, Mark D., and Gruber, Patrick R. Wed . "Method for synthesizing peptides with saccharide linked enzyme polymer conjugates". United States. https://www.osti.gov/servlets/purl/871005.
@article{osti_871005,
title = {Method for synthesizing peptides with saccharide linked enzyme polymer conjugates},
author = {Callstrom, Matthew R. and Bednarski, Mark D. and Gruber, Patrick R.},
abstractNote = {A method is disclosed for synthesizing peptides using water soluble enzyme polymer conjugates. The method comprises catalyzing the peptide synthesis with enzyme which has been covalently bonded to a polymer through at least three linkers which linkers have three or more hydroxyl groups. The enzyme is conjugated at lysines or arginines.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1997},
month = {1}
}

Patent:

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