Method for synthesizing peptides with saccharide linked enzyme polymer conjugates

Callstrom, Matthew R; Bednarski, Mark D; Gruber, Patrick R

Title: Method for synthesizing peptides with saccharide linked enzyme polymer conjugates

Patent · Wed Jan 01 00:00:00 EST 1997

OSTI ID:871005

Callstrom, Matthew R ^[1]; Bednarski, Mark D ^[2]; Gruber, Patrick R ^[3]

Columbus, OH
Berkeley, CA
St. Paul, MN

A method is disclosed for synthesizing peptides using water soluble enzyme polymer conjugates. The method comprises catalyzing the peptide synthesis with enzyme which has been covalently bonded to a polymer through at least three linkers which linkers have three or more hydroxyl groups. The enzyme is conjugated at lysines or arginines.

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

DOE Contract Number:: AC03-76SF00098

Assignee:: Cargill, Incorporated (Minneapolis, MN)

Patent Number(s):: US 5639633

OSTI ID:: 871005

Country of Publication:: United States

Language:: English

References (57)

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method
synthesizing
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comprises
catalyzing
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covalently
bonded
linkers
hydroxyl
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lysines
arginines
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method comprises
covalently bonded
polymer conjugates
method comprise
synthesizing peptides
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Title: Method for synthesizing peptides with saccharide linked enzyme polymer conjugates

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