Processes for producing polyhydroxybutyrate and related polyhydroxyalkanoates in the plastids of higher plants
Patent
·
OSTI ID:870857
- Portola Valley, CA
- Palo Alto, CA
The present invention relates to a process for producing poly-D-(-)-3-hydroxybutyric acid (PHB) and related polyhydroxyalkanoates (PHA) in the plastids of plants. The production of PHB is accomplished by genetically transforming plants with modified genes from microorganisms. The genes encode the enzymes required to synthesize PHB from acetyl-CoA or related metabolites and are fused with additional plant sequences for targeting the enzymes to the plastid.
- Research Organization:
- MICHIGAN STATE UNIVERSITY
- DOE Contract Number:
- AC02-76ER01338
- Assignee:
- Board of Trustees operating Michigan State University (East Lansing, MI)
- Patent Number(s):
- US 5610041
- Application Number:
- 08/254,357
- OSTI ID:
- 870857
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
-3-hydroxybutyric
/800/435/999/
accomplished
acetyl-coa
acid
additional
encode
enzymes
fused
genes
genetically
metabolites
microorganisms
modified
pha
phb
plant
plants
plastid
plastids
poly-d-
polyhydroxyalkanoates
polyhydroxybutyrate
process
processes
producing
production
related
related polyhydroxyalkanoates
relates
required
sequences
synthesize
targeting
transforming
/800/435/999/
accomplished
acetyl-coa
acid
additional
encode
enzymes
fused
genes
genetically
metabolites
microorganisms
modified
pha
phb
plant
plants
plastid
plastids
poly-d-
polyhydroxyalkanoates
polyhydroxybutyrate
process
processes
producing
production
related
related polyhydroxyalkanoates
relates
required
sequences
synthesize
targeting
transforming