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Self-regenerating column chromatography

Patent ·
OSTI ID:869902

The present invention provides a process for treating both cations and anions by using a self-regenerating, multi-ionic exchange resin column system which requires no separate regeneration steps. The process involves alternating ion-exchange chromatography for cations and anions in a multi-ionic exchange column packed with a mixture of cation and anion exchange resins. The multi-ionic mixed-charge resin column works as a multi-function column, capable of independently processing either cationic or anionic exchange, or simultaneously processing both cationic and anionic exchanges. The major advantage offered by the alternating multi-function ion exchange process is the self-regeneration of the resins.

Research Organization:
Monsanto Research Corporation
Sponsoring Organization:
United States Department of Energy
DOE Contract Number:
AC04-76DP00053
Assignee:
United States of America as represented by United States (Washington, DC)
Patent Number(s):
US 5419819
Application Number:
08/214,261
OSTI ID:
869902
Country of Publication:
United States
Language:
English

References (8)

Magnesium Isotope Fractionation in Cation-Exchange Chromatography journal November 1987
Displacement Band Chromatography of Hydrogen Sulfites for Enrichment of Sulfur Isotopes journal January 1993
Fractionation of Strontium Isotopes in Cation-Exchange Chromatography journal April 1992
Separation of Nitrogen Isotopes by Displacement Band Chromatography journal October 1988
Anion—cation separations on a mixed bed alumina—silica column journal January 1989
Calcium Hydroxide Isotope Effect in Calcium Isotope Enrichment by Ion Exchange journal February 1984
The Effects of Operating Parameters on Nitrogen Isotopes Separation by Displacement Band Chromatography journal October 1990
A Laboratory Method for Separating Nitrogen Isotopes by Ion Exchange 1 journal December 1955