Radiopharmaceuticals for imaging the heart
Patent
·
OSTI ID:869370
Radiopharmaceuticals for imaging myocardial tissues are prepared by forming lipophilic, cationic complexes of radioactive metal ions with metal chelating ligands comprising the Schiff base adducts of triamines and tetraamines with optionally substituted salicylaldehydes. The lipophilic, cationic, radioactive complexes of the invention exhibit high uptake and retention in myocardial tissues. Preferred gallium-68(III) complexes in accordance with this invention can be used to image the heart using positron emission tomography.
- Research Organization:
- Purdue Research Foundation, West Lafayette, IN (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- FG02-89ER60868
- Assignee:
- Purdue Research Foundation (West Lafayette, IN)
- Patent Number(s):
- 5,324,502
- Application Number:
- 07/861,778
- OSTI ID:
- 869370
- Country of Publication:
- United States
- Language:
- English
Polymeric Schiff's base chelates and their precursors: 6 Covalently polymer bound cobalt chelates from divinylsalenes and their dioxygen binding and catalytic activity
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journal | February 1984 |
Polarographische Untersuchungen an Kobaltchelatkomplexen
|
journal | October 1972 |
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