Method for detection of antibodies for metallic elements

Patent · 29 November 1993

OSTI ID:869042

Barrick, Charles W ^[1]; Clarke, Sara M ^[2]; Nordin, Carl W ^[1]

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1. Golden, CO
2. Larkspur, CO

An apparatus and method for detecting antibodies specific to non-protein antigens. The apparatus is an immunological plate containing a plurality of plastic projections coated with a non-protein material. Assays utilizing the plate are capable of stabilizing the non-protein antigens with detection levels for antibodies specific to the antigens on a nanogram level. A screening assay with the apparatus allows for early detection of exposure to non-protein materials. Specifically metallic elements are detected.

• Research Organization: ROCKWELL INTERNATIONAL CORP
• DOE Contract Number: AC04-76DP03533
• Assignee: United States of America as represented by United States (Washington, DC)
• Patent Number(s): US 5266499
• Application Number: 07/856,105
• OSTI ID: 869042
• Country of Publication: United States
• Language: English

Related Subjects

/436/422/
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