Method for detection of antibodies for metallic elements

Patent · Tue Nov 30 00:00:00 EST 1993

OSTI ID:869042

Barrick, Charles W ^[1]; Clarke, Sara M ^[2]; Nordin, Carl W ^[1]

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1. Golden, CO
2. Larkspur, CO

An apparatus and method for detecting antibodies specific to non-protein antigens. The apparatus is an immunological plate containing a plurality of plastic projections coated with a non-protein material. Assays utilizing the plate are capable of stabilizing the non-protein antigens with detection levels for antibodies specific to the antigens on a nanogram level. A screening assay with the apparatus allows for early detection of exposure to non-protein materials. Specifically metallic elements are detected.

• Research Organization: Rockwell International Corp., Canoga Park, CA (United States)
• DOE Contract Number: AC04-76DP03533
• Assignee: United States of America as represented by United States (Washington, DC)
• Patent Number(s): US 5266499
• Application Number: 07/856,105
• OSTI ID: 869042
• Country of Publication: United States
• Language: English

Related Subjects

method
detection
antibodies
metallic
elements
apparatus
detecting
specific
non-protein
antigens
immunological
plate
containing
plurality
plastic
projections
coated
material
assays
utilizing
capable
stabilizing
levels
nanogram
level
screening
assay
allows
exposure
materials
specifically
detected
plate containing
nanogram level
apparatus allows
metallic elements
antibodies specific
metallic element
/436/422/