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Title: Cell lines for the production of monoclonal antibodies to human glycophorin A

Abstract

Cloned mouse hybridoma cell lines have been established which continuously produce antibodies that differentiate between the M and N forms of human glycophorin A. These antibodies have potential application as human blood group reagents, as markers for terminally differentiated erythroid cells and as immunofluorescent labels of somatically variant human erythrocytes.

Inventors:
 [1];  [2];  [1];  [3];  [1]
  1. (Livermore, CA)
  2. (Del Mar, CA)
  3. (San Ramon, CA)
Publication Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
OSTI Identifier:
866704
Patent Number(s):
US 4767710
Assignee:
United States of America as represented by United States (Washington, DC) LLNL
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
cell; lines; production; monoclonal; antibodies; human; glycophorin; cloned; mouse; hybridoma; established; continuously; produce; differentiate; forms; potential; application; blood; reagents; markers; terminally; differentiated; erythroid; cells; immunofluorescent; labels; somatically; variant; erythrocytes; cell lines; monoclonal antibodies; fluorescent labels; human blood; human glycophorin; cell line; cloned mouse; mouse hybridoma; continuously produce; hybridoma cell; produce antibodies; /435/530/

Citation Formats

Bigbee, William L., Fong, Stella S. N., Jensen, Ronald H., Vanderlaan, Martin, and Langlois, Richard G. Cell lines for the production of monoclonal antibodies to human glycophorin A. United States: N. p., 1988. Web.
Bigbee, William L., Fong, Stella S. N., Jensen, Ronald H., Vanderlaan, Martin, & Langlois, Richard G. Cell lines for the production of monoclonal antibodies to human glycophorin A. United States.
Bigbee, William L., Fong, Stella S. N., Jensen, Ronald H., Vanderlaan, Martin, and Langlois, Richard G. Fri . "Cell lines for the production of monoclonal antibodies to human glycophorin A". United States. https://www.osti.gov/servlets/purl/866704.
@article{osti_866704,
title = {Cell lines for the production of monoclonal antibodies to human glycophorin A},
author = {Bigbee, William L. and Fong, Stella S. N. and Jensen, Ronald H. and Vanderlaan, Martin and Langlois, Richard G.},
abstractNote = {Cloned mouse hybridoma cell lines have been established which continuously produce antibodies that differentiate between the M and N forms of human glycophorin A. These antibodies have potential application as human blood group reagents, as markers for terminally differentiated erythroid cells and as immunofluorescent labels of somatically variant human erythrocytes.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Fri Jan 01 00:00:00 EST 1988},
month = {Fri Jan 01 00:00:00 EST 1988}
}

Patent:

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