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Title: Method and cell lines for the production of monoclonal antibodies to human glycophorin A

Abstract

Cloned mouse hybridoma cell lines have been established which continuously produce antibodies that differentiate between the M and N forms of human glycophorin A. These antibodies have potential application as human blood group reagents, as markers for terminally differentiated erythroid cells and as immunofluorescent labels of somatically variant human erythrocytes.

Inventors:
; ; ;
OSTI Identifier:
5433424
Application Number:
ON: DE84005984
Assignee:
EDB-84-031381
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; BLOOD GROUPS; MONOCLONAL ANTIBODIES; GLUCOPROTEINS; ERYTHROCYTES; HYBRIDOMAS; MAN; MICE; RADIOIMMUNOASSAY; ANIMAL CELLS; ANIMALS; ANTIBODIES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CARBOHYDRATES; ISOTOPE APPLICATIONS; MAMMALS; MATERIALS; ORGANIC COMPOUNDS; PRIMATES; PROTEINS; RADIOASSAY; RODENTS; SACCHARIDES; TRACER TECHNIQUES; VERTEBRATES; 550200* - Biochemistry; 550400 - Genetics; 550900 - Pathology

Citation Formats

Bigbee, W.L., Fong, S.S.N., Jensen, R.H., and Vanderlaan, M. Method and cell lines for the production of monoclonal antibodies to human glycophorin A. United States: N. p., Web.
Bigbee, W.L., Fong, S.S.N., Jensen, R.H., & Vanderlaan, M. Method and cell lines for the production of monoclonal antibodies to human glycophorin A. United States.
Bigbee, W.L., Fong, S.S.N., Jensen, R.H., and Vanderlaan, M. . "Method and cell lines for the production of monoclonal antibodies to human glycophorin A". United States.
@article{osti_5433424,
title = {Method and cell lines for the production of monoclonal antibodies to human glycophorin A},
author = {Bigbee, W.L. and Fong, S.S.N. and Jensen, R.H. and Vanderlaan, M.},
abstractNote = {Cloned mouse hybridoma cell lines have been established which continuously produce antibodies that differentiate between the M and N forms of human glycophorin A. These antibodies have potential application as human blood group reagents, as markers for terminally differentiated erythroid cells and as immunofluorescent labels of somatically variant human erythrocytes.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {},
month = {}
}