Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands
Patent
·
OSTI ID:866599
- Newton Centre, MA
- Wellesley, MA
- Needham, MA
A bisamide-bisthiol ligand containing fatty acid substituted thiol useful for producing Tc-labelled radiodiagnostic imaging agents is described. The ligand forms a complex with the radionuclide .sup.99m Tc suitable for administration as a radiopharmaceutical to obtain images of the heart for diagnosis of myocardial disfunction.
- Research Organization:
- MASSACHUSETTS INST OF TECH
- DOE Contract Number:
- AC02-76EV04115
- Assignee:
- President and Fellows of Harvard College (Cambridge, MA); Children's Medical Center Corp. (Boston, MA); Massachusetts Institute of Technology (Cambridge, MA)
- Patent Number(s):
- US 4746505
- Application Number:
- 06/727,582
- OSTI ID:
- 866599
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
/424/422/999/
99m
acid
acid substituted
acids
administration
agents
bisamide
bisamide bisthiol
bisamide-bisthiol
bisthiol
complex
containing
derived
described
diagnosis
diagnostic imaging
disfunction
fatty
fatty acid
fatty acids
forms
heart
images
imaging
imaging agent
imaging agents
ligand
ligand forms
ligands
myocardial
obtain
producing
producing tc-labelled
radiodiagnostic
radionuclide
radiopharmaceutical
substituted
suitable
tc
tc-labelled
tc-labelled radiodiagnostic
technetium
technetium radiodiagnostic
thiol
useful
99m
acid
acid substituted
acids
administration
agents
bisamide
bisamide bisthiol
bisamide-bisthiol
bisthiol
complex
containing
derived
described
diagnosis
diagnostic imaging
disfunction
fatty
fatty acid
fatty acids
forms
heart
images
imaging
imaging agent
imaging agents
ligand
ligand forms
ligands
myocardial
obtain
producing
producing tc-labelled
radiodiagnostic
radionuclide
radiopharmaceutical
substituted
suitable
tc
tc-labelled
tc-labelled radiodiagnostic
technetium
technetium radiodiagnostic
thiol
useful