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NMR chemical shifts in amino acids: Effects of environments, electric field, and amine group rotation

Journal Article · · Solid State Communications
OSTI ID:841099

The authors present calculations of NMR chemical shifts in crystalline phases of some representative amino acids such as glycine, alanine, and alanyl-alanine. To get an insight on how different environments affect the chemical shifts, they study the transition from the crystalline phase to completely isolated molecules of glycine. In the crystalline limit, the shifts are dominated by intermolecular hydrogen-bonds. In the molecular limit, however, dipole electric field effects dominate the behavior of the chemical shifts. They show that it is necessary to average the chemical shifts in glycine over geometries. Tensor components are analyzed to get the angle dependent proton chemical shifts, which is a more refined characterization method.

Research Organization:
Ernest Orlando Lawrence Berkeley National Laboratory, Berkeley, CA (US)
Sponsoring Organization:
USDOE. Office of Advanced Scientific Computing Research. Mathematical Information and Computational Sciences Division; National Science Foundation Grant DMR-9520554 (US)
DOE Contract Number:
AC03-76SF00098
OSTI ID:
841099
Report Number(s):
LBNL--51020
Journal Information:
Solid State Communications, Journal Name: Solid State Communications Journal Issue: 1 Vol. 131
Country of Publication:
United States
Language:
English

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